Using chirality to influence supramolecular gelation

Kate McAulay, Bart Dietrich, Hao Su, Michael T. Scott, Sarah Rogers, Youssra K. Al-Hilaly, Honggang Cui, Louise C. Serpell, Annela M. Seddon, Emily R. Draper, Dave J. Adams

Research output: Contribution to journalArticle

44 Downloads (Pure)

Abstract

Most low molecular weight gelators are chiral, with racemic mixtures often unable to form gels. Here, we show an example where all enantiomers, diastereomers and racemates of a single functionalized dipeptide can form gels. At high pH, different self-assembled aggregates are formed and these directly template the structures formed in the gel. Hence, solutions and gels with different properties can be accessed simply by varying the chirality. This opens up new design rules for the field.
Original languageEnglish
Pages (from-to)7801-7806
Number of pages6
JournalChemical Science
Volume10
Issue number33
DOIs
Publication statusPublished - 3 Jul 2019

Keywords

  • hydrogel
  • chiral
  • small angle scattering

Fingerprint Dive into the research topics of 'Using chirality to influence supramolecular gelation'. Together they form a unique fingerprint.

  • Cite this

    McAulay, K., Dietrich, B., Su, H., Scott, M. T., Rogers, S., Al-Hilaly, Y. K., Cui, H., Serpell, L. C., Seddon, A. M., Draper, E. R., & Adams, D. J. (2019). Using chirality to influence supramolecular gelation. Chemical Science, 10(33), 7801-7806. https://doi.org/10.1039/C9SC02239B