Use of laboratory-based surveillance data to estimate the number of people chronically infected with hepatitis B living in Scotland

Christian Schnier, Lesley Wallace, Kate Templeton, Celia Aitken, Rory Gunson, Pamela Molyneaux, Paul McIntyre, Christopher Povey, David Goldberg, Sharon Hutchinson

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Abstract

It is paramount to understand the epidemiology of chronic hepatitis B to inform national policies on vaccination and screening/testing as well as cost-effectiveness studies. However, information on the national (Scottish) prevalence of chronic hepatitis B by ethnic group is lacking. To estimate the number of people with chronic hepatitis B in Scotland in 2009 by ethnicity, gender and age, the test data from virology laboratories in the four largest cities in Scotland were combined with estimates of the ethnic distribution of the Scottish population. Ethnicity in both the test data and the Scottish population was derived using a name-based ethnicity classification software (OnoMAP; Publicprofiler Ltd, UK). For 2009, we estimated 8720 [95% confidence interval (CI) 7490-10 230] people aged 15 years were living with chronic hepatitis B infection in Scotland. This corresponds to 0.2% (95% CI 0.17-0.24) of the Scottish population aged 15 years.
Original languageEnglish
Pages (from-to)2121-2130
Number of pages10
JournalEpidemiology and Infection
Volume142
Issue number10
Early online date17 Dec 2013
DOIs
Publication statusPublished - Oct 2014

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Chronic Hepatitis B
Scotland
Hepatitis B
Confidence Intervals
Virology
Ethnic Groups
Population
Cost-Benefit Analysis
Names
Vaccination
Epidemiology
Software
Demography
Infection

Keywords

  • Hepatitis B
  • surveillance
  • public health
  • epidemiology

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Schnier, C., Wallace, L., Templeton, K., Aitken, C., Gunson, R., Molyneaux, P., ... Hutchinson, S. (2014). Use of laboratory-based surveillance data to estimate the number of people chronically infected with hepatitis B living in Scotland. Epidemiology and Infection, 142(10), 2121-2130. https://doi.org/10.1017/S0950268813003105
Schnier, Christian ; Wallace, Lesley ; Templeton, Kate ; Aitken, Celia ; Gunson, Rory ; Molyneaux, Pamela ; McIntyre, Paul ; Povey, Christopher ; Goldberg, David ; Hutchinson, Sharon. / Use of laboratory-based surveillance data to estimate the number of people chronically infected with hepatitis B living in Scotland. In: Epidemiology and Infection. 2014 ; Vol. 142, No. 10. pp. 2121-2130.
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Schnier, C, Wallace, L, Templeton, K, Aitken, C, Gunson, R, Molyneaux, P, McIntyre, P, Povey, C, Goldberg, D & Hutchinson, S 2014, 'Use of laboratory-based surveillance data to estimate the number of people chronically infected with hepatitis B living in Scotland', Epidemiology and Infection, vol. 142, no. 10, pp. 2121-2130. https://doi.org/10.1017/S0950268813003105

Use of laboratory-based surveillance data to estimate the number of people chronically infected with hepatitis B living in Scotland. / Schnier, Christian; Wallace, Lesley; Templeton, Kate; Aitken, Celia; Gunson, Rory; Molyneaux, Pamela; McIntyre, Paul; Povey, Christopher ; Goldberg, David; Hutchinson, Sharon.

In: Epidemiology and Infection, Vol. 142, No. 10, 10.2014, p. 2121-2130.

Research output: Contribution to journalArticle

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AU - Wallace, Lesley

AU - Templeton, Kate

AU - Aitken, Celia

AU - Gunson, Rory

AU - Molyneaux, Pamela

AU - McIntyre, Paul

AU - Povey, Christopher

AU - Goldberg, David

AU - Hutchinson, Sharon

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AB - It is paramount to understand the epidemiology of chronic hepatitis B to inform national policies on vaccination and screening/testing as well as cost-effectiveness studies. However, information on the national (Scottish) prevalence of chronic hepatitis B by ethnic group is lacking. To estimate the number of people with chronic hepatitis B in Scotland in 2009 by ethnicity, gender and age, the test data from virology laboratories in the four largest cities in Scotland were combined with estimates of the ethnic distribution of the Scottish population. Ethnicity in both the test data and the Scottish population was derived using a name-based ethnicity classification software (OnoMAP; Publicprofiler Ltd, UK). For 2009, we estimated 8720 [95% confidence interval (CI) 7490-10 230] people aged 15 years were living with chronic hepatitis B infection in Scotland. This corresponds to 0.2% (95% CI 0.17-0.24) of the Scottish population aged 15 years.

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Schnier C, Wallace L, Templeton K, Aitken C, Gunson R, Molyneaux P et al. Use of laboratory-based surveillance data to estimate the number of people chronically infected with hepatitis B living in Scotland. Epidemiology and Infection. 2014 Oct;142(10):2121-2130. https://doi.org/10.1017/S0950268813003105