TY - JOUR
T1 - Urinary incontinence in men after formal one-to-one pelvic-floor muscle training following radical prostatectomy or transurethral resection of the prostate (MAPS): two parallel randomised controlled trials
AU - Glazener, Cathryn
AU - Boachie, Charles
AU - Buckley, Brian
AU - Cochran, Claire
AU - Dorey, Grace
AU - Grant, Adrian
AU - Hagen, Suzanne
AU - Kilonzo, Mary
AU - McDonald, Alison
AU - McPherson, Gladys
N1 - <p>Originally published in: The Lancet (2011), available online ahead of print from publisher's website: <a href="http://dx.doi.org/10.1016/S0140-6736(11)60751-4">http://dx.doi.org/10.1016/S0140-6736(11)60751-4</a>. Copyright Elsevier, reproduced in line with publisher copyright policy.</p>
PY - 2011/7
Y1 - 2011/7
N2 - Urinary incontinence is common immediately after prostate surgery. Men are often advised to do pelvic-floor exercises, but evidence to support this is inconclusive. Our aim was to establish if formal one-to-one pelvic floor muscle training reduces incontinence. We undertook two randomised trials in men in the UK who were incontinent 6 weeks after radical prostatectomy (trial 1) or transurethral resection of the prostate (TURP; trial 2) to compare four sessions with a therapist over 3 months with standard care and lifestyle advice only. Randomisation was by remote computer allocation. Our primary endpoints, collected via postal questionnaires, were participants' reports of urinary incontinence and incremental cost per quality-adjusted life year (QALY) after 12 months. Group assignment was masked from outcome assessors, but this masking was not possible for participants or caregivers. We used intention-to-treat analyses to compare the primary outcome at 12 months. This study is registered, number ISRCTN87696430.
AB - Urinary incontinence is common immediately after prostate surgery. Men are often advised to do pelvic-floor exercises, but evidence to support this is inconclusive. Our aim was to establish if formal one-to-one pelvic floor muscle training reduces incontinence. We undertook two randomised trials in men in the UK who were incontinent 6 weeks after radical prostatectomy (trial 1) or transurethral resection of the prostate (TURP; trial 2) to compare four sessions with a therapist over 3 months with standard care and lifestyle advice only. Randomisation was by remote computer allocation. Our primary endpoints, collected via postal questionnaires, were participants' reports of urinary incontinence and incremental cost per quality-adjusted life year (QALY) after 12 months. Group assignment was masked from outcome assessors, but this masking was not possible for participants or caregivers. We used intention-to-treat analyses to compare the primary outcome at 12 months. This study is registered, number ISRCTN87696430.
KW - urinary incontinence in men
KW - prostatectomy
KW - prostate surgery
KW - pelvic-floor muscle training
UR - http://www.scopus.com/inward/record.url?scp=79960709479&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(11)60751-4
DO - 10.1016/S0140-6736(11)60751-4
M3 - Article
SN - 0140-6736
VL - 378
SP - 328
EP - 337
JO - The Lancet
JF - The Lancet
IS - 9788
ER -