Abstract
Hepatitis E virus (HEV)-positive plasma donations, identified by a plasma mini-pool screening approach, were analysed using serological methods for the presence of anti-HEV IgM and IgG. Avidity testing was performed on the IgG-reactive donations. Anti-HEV IgG with high avidity was observed in two donors together with high viral loads, but with the absence of anti-HEV IgM. These data are suggestive of re-infection in a small proportion of plasma donors, which has not previously been reported.
Original language | English |
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Pages (from-to) | 406-409 |
Number of pages | 4 |
Journal | Vox Sanguinis |
Volume | 109 |
Issue number | 4 |
Early online date | 29 May 2015 |
DOIs | |
Publication status | Published - Nov 2015 |
Keywords
- HEV testing
- NAT testing
- avidity test
- reinfection risk