The use of urea-based creams in the prevention of diabetic ulceration

Jackie Locke, Stuart Baird, Gordon Hendry

Research output: Contribution to journalArticlepeer-review


Dermatological conditions such as anhydrosis (lack of sweat production), xerosis (abnormal dryness and scaling of skin), callous and fissuring increase the risk of ulceration in diabetic autonomic neuropathy. Patient education and topical application of emollients are effective in the prevention of these conditions, and may reduce the associated risk of ulceration. However, patient compliance is often difficult to achieve and multiple daily applications of emollient are considered demanding and inconvenient. With this in view, the use of an emollient that is effective in preventing dermatological conditions with a once daily topical application may improve patient compliance and reduce the risk of diabetic ulceration.
Original languageEnglish
Pages (from-to)26-32
Number of pages7
JournalDermatological Nursing
Issue number2
Publication statusPublished - Jun 2012


  • diabetic autonomic neuropathy
  • ulceration
  • urea-based emollients
  • patient compliance
  • targeted preventative
  • intervention

ASJC Scopus subject areas

  • Podiatry


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