The systemic inflammatory response following hand instrumentation versus ultrasonic instrumentation—A randomized controlled trial

William Johnston, Michael Paterson, Krystyna Piela, Emily Davison, Annabel Simpson, Marilyn Goulding, Gordon Ramage, Andrea Sherriff, Shauna Culshaw*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)
4 Downloads (Pure)

Abstract

Objective: This study sought to investigate whether the immediate systemic inflammatory response following full-mouth debridement differs following use of hand compared with ultrasonic instruments. Methods: Thirty-nine periodontitis patients were randomized to treatment with full-mouth debridement using either hand or ultrasonic instrumentation completed within 24 hr. Serum and periodontal clinical parameters were collected at baseline, day 1, day 7 and day 90 post-treatment. Differences in systemic inflammatory markers were assessed using general linear models at each timepoint, corrected for age, gender, smoking status, body mass index and baseline levels of each marker. Results: Across all patients, serum C-reactive protein increased at day 1, with no differences between hand and ultrasonic groups (p(adjusted) =.22). There was no difference between groups in interleukin-6 (p(adjusted) =.29) or tumour necrosis factor α (p(adjusted) =.53) at day 1. Inflammatory markers returned to baseline levels by day 7. Treatment resulted in equal and marked improvements in clinical parameters in both groups; however, total treatment time was on average shorter for ultrasonic instruments (p(adjusted) =.002). Conclusions: Ultrasonic instrumentation resulted in shorter treatment time with comparable clinical outcomes. Levels of serum C-reactive protein at day 1 were similar following debridement with hand or ultrasonic instruments.

Original languageEnglish
Pages (from-to)1087-1097
Number of pages11
JournalJournal of Clinical Periodontology
Volume47
Issue number9
Early online date27 Jul 2020
DOIs
Publication statusPublished - Sep 2020

Keywords

  • hand instruments
  • periodontal treatment
  • randomized controlled trial
  • systemic inflammation
  • ultrasonic instruments

ASJC Scopus subject areas

  • Periodontics

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