The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis

Douglas Bovell; Alison MacDonald; Barbara A. Meyer; Alistair Corbett; William MacLaren; Susan L. Holmes; Mark Harker

doi:10.1111/j.1600-0625.2011.01361.x

The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis

Douglas Bovell, Alison MacDonald, Barbara A. Meyer, Alistair Corbett, William MacLaren, Susan L. Holmes, Mark Harker

SHLS School Office

Research output: Contribution to journal › Article

Abstract

Primary hyperhidrosis is characterized by excessive sweating in palmar, plantar and axillary body regions. Gland hypertrophy and the existence of a third type of sweat gland, the apoeccrine gland, with high fluid transporting capabilities have been suggested as possible causes. This study investigated whether sweat glands were hypertrophied in axillary hyperhidrotic patients and if mechanisms associated with fluid transport were found in all types of axillary sweat glands. The occurrence of apoeccrine sweat glands was also investigated. Axillary skin biopsies from control and hyperhidrosis patients were examined using immunohistochemistry, image analysis and immunofluorescence microscopy.

Original language	English
Pages (from-to)	1017–1020
Number of pages	4
Journal	Experimental Dermatology
Volume	20
Issue number	12
DOIs	https://doi.org/10.1111/j.1600-0625.2011.01361.x
Publication status	Published - Dec 2011

Keywords

eccrine sweat gland
hyperhidrosis
immunohistochemistry

Documents and Links

10.1111/j.1600-0625.2011.01361.x

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Bovell, D., MacDonald, A., Meyer, B. A., Corbett, A., MacLaren, W., Holmes, S. L., & Harker, M. (2011). The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis. Experimental Dermatology, 20(12), 1017–1020. https://doi.org/10.1111/j.1600-0625.2011.01361.x

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The secretory clear cell of the eccrine sweat gland as the probable source of excess sweat production in hyperhidrosis. / Bovell, Douglas; MacDonald, Alison; Meyer, Barbara A.; Corbett, Alistair; MacLaren, William; Holmes, Susan L.; Harker, Mark.

In: Experimental Dermatology, Vol. 20, No. 12, 12.2011, p. 1017–1020.

Research output: Contribution to journal › Article

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