Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 398-404 |
| Number of pages | 7 |
| Journal | European Journal of Gastroenterology and Hepatology |
| Volume | 28 |
| Issue number | 4 |
| Early online date | 21 Dec 2015 |
| DOIs | |
| Publication status | Published - Apr 2016 |
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Keywords
- thrombocytopenia
- Hepatitis C
- antiviral therapy
Cite this
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The prevalence and impact of thrombocytopenia, anaemia and leucopenia on sustained virological response in patients receiving hepatitis C therapy: evidence from a large ‘real world’ cohort. / Wang, Huan; Innes, Hamish; Hutchinson, Sharon; Goldberg, David; Allen, Samuel; Barclay, Stephen T.; Bramley, Peter; Fox, Raymond; Fraser, Andrew; Hayes, Peter ; Kennedy, Nicholas; Mills, Peter R.; Dillon, John F.
In: European Journal of Gastroenterology and Hepatology, Vol. 28 , No. 4, 04.2016, p. 398-404.Research output: Contribution to journal › Article
TY - JOUR
T1 - The prevalence and impact of thrombocytopenia, anaemia and leucopenia on sustained virological response in patients receiving hepatitis C therapy: evidence from a large ‘real world’ cohort
AU - Wang, Huan
AU - Innes, Hamish
AU - Hutchinson, Sharon
AU - Goldberg, David
AU - Allen, Samuel
AU - Barclay, Stephen T.
AU - Bramley, Peter
AU - Fox, Raymond
AU - Fraser, Andrew
AU - Hayes, Peter
AU - Kennedy, Nicholas
AU - Mills, Peter R.
AU - Dillon, John F.
N1 - Out-with REF monitoring period (online pub Dec15) Acceptance date unknown AAM uploaded 9-3-16; 12m embargo required by publisher applied to online pub date - ET 18-4-16
PY - 2016/4
Y1 - 2016/4
N2 - The aim of the study was to explore the extent of thrombocytopenia (TCP), anaemia and leucopenia in patients with hepatitis C and evaluate how they impact the management of antiviral therapy, the attainment of sustained virological response (SVR), and some therapy-related adverse events. The Scottish Hepatitis C Clinical Database was used in this retrospective study. The prevalence of TCP, anaemia and leucopenia was evaluated. The impact of the three deficiencies on antiviral therapy management, serious adverse events and SVR attainment was assessed in patients who received therapy.
AB - The aim of the study was to explore the extent of thrombocytopenia (TCP), anaemia and leucopenia in patients with hepatitis C and evaluate how they impact the management of antiviral therapy, the attainment of sustained virological response (SVR), and some therapy-related adverse events. The Scottish Hepatitis C Clinical Database was used in this retrospective study. The prevalence of TCP, anaemia and leucopenia was evaluated. The impact of the three deficiencies on antiviral therapy management, serious adverse events and SVR attainment was assessed in patients who received therapy.
KW - thrombocytopenia
KW - Hepatitis C
KW - antiviral therapy
U2 - 10.1097/MEG.0000000000000556
DO - 10.1097/MEG.0000000000000556
M3 - Article
VL - 28
SP - 398
EP - 404
JO - European Journal of Gastroenterology and Hepatology
JF - European Journal of Gastroenterology and Hepatology
SN - 0954-691X
IS - 4
ER -