TY - CHAP
T1 - The oral mucosa-fungi interactome
AU - Neelakantan, Prasanna
AU - Kalimuthu, Shanthini
AU - Pudipeddi, Akhila
AU - Krom, Bastiaan P.
AU - Ramage, Gordon
AU - Butcher, Mark
AU - Brown, Jason L.
PY - 2025/5/31
Y1 - 2025/5/31
N2 - Human beings are indwelled by a wide array of cellular microbes, building up their core microbiome. Amongst these, bacterial constituents comprise about 99% of the population. The remaining small, yet diverse population of microbes are termed the ‘rare-biosphere’. The eukaryotic yeasts contribute a substantial population within the rare biosphere. Despite the reduced abundance, yeasts/fungi cause a wide range of infections ranging from superficial to deep-seated, invasive, and life-threatening infections. This chapter provides an in-depth view of the role of fungi, specifically Candida albicans, in oral health and disease. We highlight the interactive profiles between the mycobiome and host oral tissues including study models for future state-of-the-art research in this important area.
AB - Human beings are indwelled by a wide array of cellular microbes, building up their core microbiome. Amongst these, bacterial constituents comprise about 99% of the population. The remaining small, yet diverse population of microbes are termed the ‘rare-biosphere’. The eukaryotic yeasts contribute a substantial population within the rare biosphere. Despite the reduced abundance, yeasts/fungi cause a wide range of infections ranging from superficial to deep-seated, invasive, and life-threatening infections. This chapter provides an in-depth view of the role of fungi, specifically Candida albicans, in oral health and disease. We highlight the interactive profiles between the mycobiome and host oral tissues including study models for future state-of-the-art research in this important area.
U2 - 10.1007/978-3-031-82202-5_7
DO - 10.1007/978-3-031-82202-5_7
M3 - Chapter (peer-reviewed)
SN - 9783031822018
T3 - Springer Series on Biofilms
SP - 189
EP - 231
BT - Oral Biofilms in Health and Disease
A2 - Koo, Hyun (Michel)
A2 - Jakubovics, Nicholas S.
A2 - Krom, Bastiaan P.
PB - Springer, Cham
ER -
