The influence of gender on the development of pulmonary arterial hypertension

Yvonne Dempsie; Margaret R. MacLean

doi:10.1113/expphysiol.2012.069120

The influence of gender on the development of pulmonary arterial hypertension

Yvonne Dempsie, Margaret R. MacLean

Biological and Biomedical Sciences

Research output: Contribution to journal › Literature review › peer-review

Abstract

Pulmonary arterial hypertension (PAH) in its idiopathic and familial forms occurs more frequently in females than in males (>2:1 incidence ratio). Experimentally, however, female gender and oestrogens can both protect against and exacerbate PAH. This review will discuss our current understanding of the influence of sex hormones on the development of PAH.

Original language	English
Pages (from-to)	1257-1261
Number of pages	5
Journal	Experimental Physiology
Volume	98
Early online date	26 Apr 2013
DOIs	https://doi.org/10.1113/expphysiol.2012.069120
Publication status	Published - Aug 2013

Keywords

pulmonary arterial hypertension
PAH
oestrogens
sex hormones

Documents and Links

10.1113/expphysiol.2012.069120

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KW - oestrogens

KW - sex hormones

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