Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 1257-1261 |
| Number of pages | 5 |
| Journal | Experimental Physiology |
| Volume | 98 |
| Early online date | 26 Apr 2013 |
| DOIs | |
| Publication status | Published - Aug 2013 |
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Keywords
- pulmonary arterial hypertension
- PAH
- oestrogens
- sex hormones
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The influence of gender on the development of pulmonary arterial hypertension. / Dempsie, Yvonne; MacLean, Margaret R.
In: Experimental Physiology, Vol. 98, 08.2013, p. 1257-1261.Research output: Contribution to journal › Literature review
TY - JOUR
T1 - The influence of gender on the development of pulmonary arterial hypertension
AU - Dempsie, Yvonne
AU - MacLean, Margaret R.
N1 - check back for print reference details, early online ET 5-7-13
PY - 2013/8
Y1 - 2013/8
N2 - Pulmonary arterial hypertension (PAH) in its idiopathic and familial forms occurs more frequently in females than in males (>2:1 incidence ratio). Experimentally, however, female gender and oestrogens can both protect against and exacerbate PAH. This review will discuss our current understanding of the influence of sex hormones on the development of PAH.
AB - Pulmonary arterial hypertension (PAH) in its idiopathic and familial forms occurs more frequently in females than in males (>2:1 incidence ratio). Experimentally, however, female gender and oestrogens can both protect against and exacerbate PAH. This review will discuss our current understanding of the influence of sex hormones on the development of PAH.
KW - pulmonary arterial hypertension
KW - PAH
KW - oestrogens
KW - sex hormones
U2 - 10.1113/expphysiol.2012.069120
DO - 10.1113/expphysiol.2012.069120
M3 - Literature review
VL - 98
SP - 1257
EP - 1261
JO - Experimental Physiology
JF - Experimental Physiology
SN - 0958-0670
ER -