Patients living with human immunodeficiency virus (HIV) infection who are treated with highly active antiretroviral therapy (HAART) often ex-perience metabolic changes that have an adverse effect on their over-all health status. This review will assess the effect of aerobic exercises on the lipid profile of individuals with HIV infection undergoing HAART. Cochrane Library, MEDLINE, CINAHL (Cumulative index to Nursing and Allied Health Literature), OVID, ProQuest, AMED (Allied and Comple-mentary Medicine Database), PsycINFO, Web of Science Core Collec-tion and Pedro databases will be searched until June 2018. Studies that investigated the effects of aerobic exercises on the lipid profile of HAART treated patients with HIV will be included. Two reviewers will screen all articles for eligibility and independently evaluate the risk of bias, complete quality assessment and extract data for all included arti-cles. Homogenous quantitative outcome data will be analyzed using a random effect model of meta-analysis with results presented as relative risk for dichotomous variable and standardized mean for continuous variable. Heterogeneous qualitative data will be analyzed using narra-tive synthesis. This systematic review will provide evidence about the effectiveness of aerobic exercises in managing HAART related dyslip-idemia in patients with HIV infection and thus provide the impetus for more structured exercise interventions.
- Aerobic exercises
- Highly active retroviral ther-apy
- Human immunodeficiency virus infection
- Systematic review
ASJC Scopus subject areas
- Physical Therapy, Sports Therapy and Rehabilitation
- Orthopedics and Sports Medicine