The effect of aerobic exercises on lipid profile of patients with human immunodeficiency virus infection undergoing highly active antiretroviral therapy: a protocol for a systematic review

Ebuka Miracle Anieto*, Chidimma Amarachukwu Nwankwo, Samuel Ugochukwu Jumbo, Michael Ebe Kalu

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Patients living with human immunodeficiency virus (HIV) infection who are treated with highly active antiretroviral therapy (HAART) often ex-perience metabolic changes that have an adverse effect on their over-all health status. This review will assess the effect of aerobic exercises on the lipid profile of individuals with HIV infection undergoing HAART. Cochrane Library, MEDLINE, CINAHL (Cumulative index to Nursing and Allied Health Literature), OVID, ProQuest, AMED (Allied and Comple-mentary Medicine Database), PsycINFO, Web of Science Core Collec-tion and Pedro databases will be searched until June 2018. Studies that investigated the effects of aerobic exercises on the lipid profile of HAART treated patients with HIV will be included. Two reviewers will screen all articles for eligibility and independently evaluate the risk of bias, complete quality assessment and extract data for all included arti-cles. Homogenous quantitative outcome data will be analyzed using a random effect model of meta-analysis with results presented as relative risk for dichotomous variable and standardized mean for continuous variable. Heterogeneous qualitative data will be analyzed using narra-tive synthesis. This systematic review will provide evidence about the effectiveness of aerobic exercises in managing HAART related dyslip-idemia in patients with HIV infection and thus provide the impetus for more structured exercise interventions.

Original languageEnglish
Pages (from-to)559-565
Number of pages7
JournalJournal of Exercise Rehabilitation
Volume14
Issue number4
Early online date24 Aug 2018
DOIs
Publication statusPublished - Aug 2018
Externally publishedYes

Keywords

  • Aerobic exercises
  • Dyslipidemia
  • Highly active retroviral ther-apy
  • Human immunodeficiency virus infection
  • Lipids
  • Systematic review

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine

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