Tear physiology in dry eye associated with chronic GVHD

Santosh Khanal, Alan Tomlinson

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


The purpose of this study was to compare tear physiology characteristics of chronic GVHD (cGVHD)-associated dry eye to dry eye caused by Sjogren's syndrome (SS), a extreme form of aqueous-deficient dry eye, and meibomian gland dysfunction (MGD), the major cause of evaporative dry eye. Tear turnover rate, evaporation and osmolarity along with meibomian gland dropout and lipid layer interferometric patterns were assessed in the right eyes of 12 patients with dry eye associated with cGVHD, 12 age-matched patients with SS and 12 age-sex matched subjects with MGD.
Original languageEnglish
Pages (from-to)115-119
Number of pages5
JournalBone Marrow Transplantation
Issue number1
Publication statusPublished - Jan 2012


  • vision sciences
  • tear physiology
  • dry eye


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