Tear fluid biomarker profiling: a review of multiplex bead analysis

Suzanne Hagan; Alan Tomlinson

doi:10.1016/j.jtos.2013.04.004

Tear fluid biomarker profiling: a review of multiplex bead analysis

Suzanne Hagan, Alan Tomlinson

Vision Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Developments in the field of tear film protein profiling are reviewed, including the advantages and disadvantages of the multiplex bead array technique and its potential for identifying biomarkers of ocular surface disease. Commercial kits, which specifically employ 96-well plates with polystyrene microspheres and magnetic beads, and sensitivity variations between them are discussed.

Original language	English
Pages (from-to)	219-235
Number of pages	17
Journal	The Ocular Surface
Volume	11
Issue number	4
DOIs	https://doi.org/10.1016/j.jtos.2013.04.004
Publication status	Published - Oct 2013

Keywords

dry eye
tear fluid
multiplex bead array
biomarkers

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10.1016/j.jtos.2013.04.004

Cite this

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title = "Tear fluid biomarker profiling: a review of multiplex bead analysis",

abstract = "Developments in the field of tear film protein profiling are reviewed, including the advantages and disadvantages of the multiplex bead array technique and its potential for identifying biomarkers of ocular surface disease. Commercial kits, which specifically employ 96-well plates with polystyrene microspheres and magnetic beads, and sensitivity variations between them are discussed.",

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AB - Developments in the field of tear film protein profiling are reviewed, including the advantages and disadvantages of the multiplex bead array technique and its potential for identifying biomarkers of ocular surface disease. Commercial kits, which specifically employ 96-well plates with polystyrene microspheres and magnetic beads, and sensitivity variations between them are discussed.

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Tear fluid biomarker profiling: a review of multiplex bead analysis

Abstract

Keywords

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