Tear fluid biomarker profiling: a review of multiplex bead analysis

Research output: Contribution to journalArticle

Abstract

Developments in the field of tear film protein profiling are reviewed, including the advantages and disadvantages of the multiplex bead array technique and its potential for identifying biomarkers of ocular surface disease. Commercial kits, which specifically employ 96-well plates with polystyrene microspheres and magnetic beads, and sensitivity variations between them are discussed.
Original languageEnglish
Pages (from-to)219-235
Number of pages17
JournalThe Ocular Surface
Volume11
Issue number4
DOIs
Publication statusPublished - Oct 2013

Keywords

  • dry eye
  • tear fluid
  • multiplex bead array
  • biomarkers

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