Surface disinfection challenges for Candida auris: an in-vitro study

R. Kean; L. Sherry; E. Townsend; E. McKloud; B. Short; A. Akinbobola; W.G. MacKay; C. Williams; B.L. Jones; G. Ramage

doi:10.1016/j.jhin.2017.11.015

Surface disinfection challenges for Candida auris: an in-vitro study

R. Kean, L. Sherry, E. Townsend, E. McKloud, B. Short, A. Akinbobola, W.G. MacKay, C. Williams, B.L. Jones, G. Ramage

Biological and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

103 Downloads (Pure)

Abstract

The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.

Original language	English
Pages (from-to)	433-436
Number of pages	4
Journal	Journal of Hospital Infection
Volume	98
Issue number	4
Early online date	7 Dec 2017
DOIs	https://doi.org/10.1016/j.jhin.2017.11.015
Publication status	Published - 1 Apr 2018

Keywords

disinfection
Candida auris
surface

Documents and Links

10.1016/j.jhin.2017.11.015

Kean, R. et al (2018) Surface disinfection challenges for Candida auris: an in vitro study
© 2018 Elsevier. Reproduced in accordance with the publisher's self-archiving policy. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
Accepted author manuscript, 453 KBLicence: CC BY-NC-ND

http://eprints.gla.ac.uk/167786/Licence: CC BY-NC-ND

Fingerprint Dive into the research topics of 'Surface disinfection challenges for Candida auris: an in-vitro study'. Together they form a unique fingerprint.

Cite this

@article{8292a85d64a04990bfc0cc3052703131,

title = "Surface disinfection challenges for Candida auris: an in-vitro study",

abstract = "The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.",

keywords = "disinfection, Candida auris, surface",

author = "R. Kean and L. Sherry and E. Townsend and E. McKloud and B. Short and A. Akinbobola and W.G. MacKay and C. Williams and B.L. Jones and G. Ramage",

note = "Funding: European Society of Clinical Microbiology and Infectious Diseases financial support for L.S. Acceptance from webpage AAM requested; version queried 20/11/18 DC AAM from Enlighten repository. Author start date at GCU is after acceptance > apply exception 254a. ET 13/11/19 ",

year = "2018",

month = apr,

day = "1",

doi = "10.1016/j.jhin.2017.11.015",

language = "English",

volume = "98",

pages = "433--436",

journal = "Journal of Hospital Infection",

issn = "0195-6701",

publisher = "Elsevier B.V.",

number = "4",

}

TY - JOUR

T1 - Surface disinfection challenges for Candida auris: an in-vitro study

AU - Kean, R.

AU - Sherry, L.

AU - Townsend, E.

AU - McKloud, E.

AU - Short, B.

AU - Akinbobola, A.

AU - MacKay, W.G.

AU - Williams, C.

AU - Jones, B.L.

AU - Ramage, G.

N1 - Funding: European Society of Clinical Microbiology and Infectious Diseases financial support for L.S. Acceptance from webpage AAM requested; version queried 20/11/18 DC AAM from Enlighten repository. Author start date at GCU is after acceptance > apply exception 254a. ET 13/11/19

PY - 2018/4/1

Y1 - 2018/4/1

N2 - The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.

AB - The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.

KW - disinfection

KW - Candida auris

KW - surface

U2 - 10.1016/j.jhin.2017.11.015

DO - 10.1016/j.jhin.2017.11.015

M3 - Article

VL - 98

SP - 433

EP - 436

JO - Journal of Hospital Infection

JF - Journal of Hospital Infection

SN - 0195-6701

IS - 4

ER -