Surface disinfection challenges for Candida auris: an in-vitro study

R. Kean, L. Sherry, E. Townsend, E. McKloud, B. Short, A. Akinbobola, W.G. MacKay, C. Williams, B.L. Jones, G. Ramage

Research output: Contribution to journalArticle

53 Downloads (Pure)

Abstract

The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.
Original languageEnglish
Pages (from-to)433-436
Number of pages4
JournalJournal of Hospital Infection
Volume98
Issue number4
Early online date7 Dec 2017
DOIs
Publication statusPublished - Apr 2018

Fingerprint

Peracetic Acid
Sodium Hypochlorite
Disinfectants
Disinfection
Candida
Cross Infection
Yeasts
In Vitro Techniques

Keywords

  • disinfection
  • Candida auris

Cite this

Kean, R., Sherry, L., Townsend, E., McKloud, E., Short, B., Akinbobola, A., ... Ramage, G. (2018). Surface disinfection challenges for Candida auris: an in-vitro study. Journal of Hospital Infection, 98(4), 433-436. https://doi.org/10.1016/j.jhin.2017.11.015
Kean, R. ; Sherry, L. ; Townsend, E. ; McKloud, E. ; Short, B. ; Akinbobola, A. ; MacKay, W.G. ; Williams, C. ; Jones, B.L. ; Ramage, G. / Surface disinfection challenges for Candida auris: an in-vitro study. In: Journal of Hospital Infection. 2018 ; Vol. 98, No. 4. pp. 433-436.
@article{8292a85d64a04990bfc0cc3052703131,
title = "Surface disinfection challenges for Candida auris: an in-vitro study",
abstract = "The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.",
keywords = "disinfection, Candida auris",
author = "R. Kean and L. Sherry and E. Townsend and E. McKloud and B. Short and A. Akinbobola and W.G. MacKay and C. Williams and B.L. Jones and G. Ramage",
note = "Funding: European Society of Clinical Microbiology and Infectious Diseases financial support for L.S. Acceptance from webpage AAM requested; version queried 20/11/18 DC AAM from Enlighten repository. Author start date at GCU is after acceptance > apply exception 254a. ET 13/11/19",
year = "2018",
month = "4",
doi = "10.1016/j.jhin.2017.11.015",
language = "English",
volume = "98",
pages = "433--436",
journal = "Journal of Hospital Infection",
issn = "0195-6701",
publisher = "Elsevier B.V.",
number = "4",

}

Kean, R, Sherry, L, Townsend, E, McKloud, E, Short, B, Akinbobola, A, MacKay, WG, Williams, C, Jones, BL & Ramage, G 2018, 'Surface disinfection challenges for Candida auris: an in-vitro study', Journal of Hospital Infection, vol. 98, no. 4, pp. 433-436. https://doi.org/10.1016/j.jhin.2017.11.015

Surface disinfection challenges for Candida auris: an in-vitro study. / Kean, R.; Sherry, L.; Townsend, E.; McKloud, E.; Short, B.; Akinbobola, A.; MacKay, W.G.; Williams, C.; Jones, B.L.; Ramage, G.

In: Journal of Hospital Infection, Vol. 98, No. 4, 04.2018, p. 433-436.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Surface disinfection challenges for Candida auris: an in-vitro study

AU - Kean, R.

AU - Sherry, L.

AU - Townsend, E.

AU - McKloud, E.

AU - Short, B.

AU - Akinbobola, A.

AU - MacKay, W.G.

AU - Williams, C.

AU - Jones, B.L.

AU - Ramage, G.

N1 - Funding: European Society of Clinical Microbiology and Infectious Diseases financial support for L.S. Acceptance from webpage AAM requested; version queried 20/11/18 DC AAM from Enlighten repository. Author start date at GCU is after acceptance > apply exception 254a. ET 13/11/19

PY - 2018/4

Y1 - 2018/4

N2 - The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.

AB - The emerging pathogenic multidrug-resistant yeast Candida auris is an important source of healthcare-associated infections and of growing global clinical concern. The ability of this organism to survive on surfaces and withstand environmental stressors creates a challenge for eradicating it from hospitals. A panel of C. auris clinical isolates was evaluated on different surface environments against the standard disinfectant sodium hypochlorite and high-level disinfectant peracetic acid. C. auris was shown to selectively tolerate clinically relevant concentrations of sodium hypochlorite and peracetic acid in a surface-dependent manner, which may explain its ability to successfully persist within the hospital environment.

KW - disinfection

KW - Candida auris

U2 - 10.1016/j.jhin.2017.11.015

DO - 10.1016/j.jhin.2017.11.015

M3 - Article

VL - 98

SP - 433

EP - 436

JO - Journal of Hospital Infection

JF - Journal of Hospital Infection

SN - 0195-6701

IS - 4

ER -