Suggestions for the diagnosis and elimination of hepatitis E virus in pigs used for xenotransplantation

Stacey Busby, Claire Crossan, Jon Godwin, Bjoern Petersen, Cesare Galli, Emanuele Cozzi, Yasuhiro Takeuchi, Linda Scobie

Research output: Contribution to journalArticle

Abstract

The hepatitis E virus (HEV) is considered a zoonotic pathogen. In xenotransplantation, given the high prevalence of HEV infection in pigs, the risk of zoonotic transmission from a porcine source is considered high. Currently no clear data are available on how to diagnose and eliminate HEV in herds used for medical purposes and the importance of viral infection at the stage of harvest. In this study, several groups of animals currently used for medical purposes were found RNA positive in both serum and faeces for HEV genotype 3.
Original languageEnglish
Pages (from-to)188–192
Number of pages5
JournalXenotransplantation
Volume20
Issue number3
Early online date7 May 2013
DOIs
Publication statusPublished - Jun 2013

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Keywords

  • hepatitis E virus
  • xenotransplantation
  • porcine cell biology
  • viral infection

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