Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 35-40 |
| Number of pages | 6 |
| Journal | Stroke |
| Volume | 40 |
| Issue number | 1 |
| Early online date | 16 Sep 2008 |
| DOIs | |
| Publication status | Published - 2009 |
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Keywords
- acute care
- clinical trials
- stroke
- epidemiology
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Stroke outcomes in clinical trials patients deriving from different countries. / Ali, Myzoon; Atula, Sari ; Bath, Philip M.W.; Grotta, James ; Hacke, Werner; Lyden, Patrick ; Marler, John ; Sacco, Ralph ; Lees, Kennedy R.
In: Stroke, Vol. 40, No. 1, 2009, p. 35-40.Research output: Contribution to journal › Article
TY - JOUR
T1 - Stroke outcomes in clinical trials patients deriving from different countries
AU - Ali, Myzoon
AU - Atula, Sari
AU - Bath, Philip M.W.
AU - Grotta,, James
AU - Hacke, Werner
AU - Lyden, Patrick
AU - Marler, John
AU - Sacco, Ralph
AU - Lees, Kennedy R.
PY - 2009
Y1 - 2009
N2 - Stroke incidence and outcome vary widely within and across geographical locations. We examined whether differences in index stroke severity, stroke risk factors, mortality, and stroke outcome across geographical locations remain after adjusting for case mix. We analyzed 3284 patients from the Virtual International Stroke Trials Archive (VISTA). We used logistic regression to examine the incidence of mild index stroke, functional, and neurological outcomes after accounting for age, medical history, year of trial recruitment, and initial stroke severity in the functional and neurological outcome analyses. We examined mortality between geographical regions using a Cox proportional hazards model, accounting for age, initial stroke severity, medical history, and year of trial recruitment.
AB - Stroke incidence and outcome vary widely within and across geographical locations. We examined whether differences in index stroke severity, stroke risk factors, mortality, and stroke outcome across geographical locations remain after adjusting for case mix. We analyzed 3284 patients from the Virtual International Stroke Trials Archive (VISTA). We used logistic regression to examine the incidence of mild index stroke, functional, and neurological outcomes after accounting for age, medical history, year of trial recruitment, and initial stroke severity in the functional and neurological outcome analyses. We examined mortality between geographical regions using a Cox proportional hazards model, accounting for age, initial stroke severity, medical history, and year of trial recruitment.
KW - acute care
KW - clinical trials
KW - stroke
KW - epidemiology
U2 - 10.1161/STROKEAHA.108.518035
DO - 10.1161/STROKEAHA.108.518035
M3 - Article
VL - 40
SP - 35
EP - 40
JO - Stroke
JF - Stroke
SN - 0039-2499
IS - 1
ER -