Role of troponin I in active endocarditis

Richard W. Watkin, Sue Lang, Janet M. Smith, Thomas S.J. Elliott, William A. Littler

Research output: Contribution to journalArticle

Abstract

Infective endocarditis (IE) remains a disease associated with high morbidity and mortality rates. In this pilot study, the role of troponin I in IE was assessed. Myocardial involvement distal to the site of infection in IE has been previously described. Elevated troponin was demonstrated in 11 of 15 patients diagnosed with the condition. Patients diagnosed with staphylococcal endocarditis were more likely to have elevated troponin (3 of 3 patients). Patients with elevated troponin I were not more likely to need valve replacement. Troponin I levels did not predict perivalvular extension. It is hypothesized that elevated troponin I is a reflection of myocardial involvement.

Original languageEnglish
JournalThe American Journal of Cardiology
DOIs
Publication statusPublished - 1 Oct 2004

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Troponin I
Endocarditis
Troponin
Morbidity
Mortality
Infection

Keywords

  • troponin I
  • endocarditis

Cite this

Watkin, R. W., Lang, S., Smith, J. M., Elliott, T. S. J., & Littler, W. A. (2004). Role of troponin I in active endocarditis. The American Journal of Cardiology. https://doi.org/10.1016/j.amjcard.2004.07.096
Watkin, Richard W. ; Lang, Sue ; Smith, Janet M. ; Elliott, Thomas S.J. ; Littler, William A. / Role of troponin I in active endocarditis. In: The American Journal of Cardiology. 2004.
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Role of troponin I in active endocarditis. / Watkin, Richard W.; Lang, Sue; Smith, Janet M.; Elliott, Thomas S.J.; Littler, William A.

In: The American Journal of Cardiology, 01.10.2004.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Role of troponin I in active endocarditis

AU - Watkin, Richard W.

AU - Lang, Sue

AU - Smith, Janet M.

AU - Elliott, Thomas S.J.

AU - Littler, William A.

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AB - Infective endocarditis (IE) remains a disease associated with high morbidity and mortality rates. In this pilot study, the role of troponin I in IE was assessed. Myocardial involvement distal to the site of infection in IE has been previously described. Elevated troponin was demonstrated in 11 of 15 patients diagnosed with the condition. Patients diagnosed with staphylococcal endocarditis were more likely to have elevated troponin (3 of 3 patients). Patients with elevated troponin I were not more likely to need valve replacement. Troponin I levels did not predict perivalvular extension. It is hypothesized that elevated troponin I is a reflection of myocardial involvement.

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KW - endocarditis

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