Relationship between hyperacute blood pressure and outcome after ischemic stroke

Gillian Sare, Myzoon Ali, Ashfaq Shuaib, Philip M. W. Bath

    Research output: Contribution to journal › Article

    Abstract

    High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period. Analyses included 1722 patients in hyperacute trials (recruitment <8 hours) from the Virtual Stroke International Stroke Trial Archive (VISTA) Collaboration. Data on BP at enrolment and after 1, 2, 16, 24, 48, and 72 hours, neurological impairment at 7 days (NIHSS), and functional outcome at 90 days (modified Rankin scale) were assessed using logistic regression models, adjusted for confounding variables; results are for 10-mm Hg change in BP.
    Original languageEnglish
    Pages (from-to)2098-2103
    Number of pages6
    JournalStroke
    Volume40
    Issue number6
    Early online date9 Apr 2009
    DOIs
    Publication statusPublished - Jun 2009

    Fingerprint

    Stroke
    Blood Pressure
    Logistic Models
    Confounding Factors (Epidemiology)
    Hypertension

    Keywords

    • stroke
    • high blood pressure
    • ischemic stroke

    Cite this

    Sare, Gillian ; Ali, Myzoon ; Shuaib, Ashfaq ; Bath, Philip M. W. / Relationship between hyperacute blood pressure and outcome after ischemic stroke. In: Stroke. 2009 ; Vol. 40, No. 6. pp. 2098-2103.
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    abstract = "High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period. Analyses included 1722 patients in hyperacute trials (recruitment <8 hours) from the Virtual Stroke International Stroke Trial Archive (VISTA) Collaboration. Data on BP at enrolment and after 1, 2, 16, 24, 48, and 72 hours, neurological impairment at 7 days (NIHSS), and functional outcome at 90 days (modified Rankin scale) were assessed using logistic regression models, adjusted for confounding variables; results are for 10-mm Hg change in BP.",
    keywords = "stroke, high blood pressure, ischemic stroke",
    author = "Gillian Sare and Myzoon Ali and Ashfaq Shuaib and Bath, {Philip M. W.}",
    year = "2009",
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    Sare, G, Ali, M, Shuaib, A & Bath, PMW 2009, 'Relationship between hyperacute blood pressure and outcome after ischemic stroke', Stroke, vol. 40, no. 6, pp. 2098-2103. https://doi.org/10.1161/¿STROKEAHA.108.539155

    Relationship between hyperacute blood pressure and outcome after ischemic stroke. / Sare, Gillian ; Ali, Myzoon; Shuaib, Ashfaq ; Bath, Philip M. W.

    In: Stroke, Vol. 40, No. 6, 06.2009, p. 2098-2103.

    Research output: Contribution to journal › Article

    TY - JOUR

    T1 - Relationship between hyperacute blood pressure and outcome after ischemic stroke

    AU - Sare, Gillian

    AU - Ali, Myzoon

    AU - Shuaib, Ashfaq

    AU - Bath, Philip M. W.

    PY - 2009/6

    Y1 - 2009/6

    N2 - High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period. Analyses included 1722 patients in hyperacute trials (recruitment <8 hours) from the Virtual Stroke International Stroke Trial Archive (VISTA) Collaboration. Data on BP at enrolment and after 1, 2, 16, 24, 48, and 72 hours, neurological impairment at 7 days (NIHSS), and functional outcome at 90 days (modified Rankin scale) were assessed using logistic regression models, adjusted for confounding variables; results are for 10-mm Hg change in BP.

    AB - High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period. Analyses included 1722 patients in hyperacute trials (recruitment <8 hours) from the Virtual Stroke International Stroke Trial Archive (VISTA) Collaboration. Data on BP at enrolment and after 1, 2, 16, 24, 48, and 72 hours, neurological impairment at 7 days (NIHSS), and functional outcome at 90 days (modified Rankin scale) were assessed using logistic regression models, adjusted for confounding variables; results are for 10-mm Hg change in BP.

    KW - stroke

    KW - high blood pressure

    KW - ischemic stroke

    U2 - 10.1161/¿STROKEAHA.108.539155

    DO - 10.1161/¿STROKEAHA.108.539155

    M3 - Article

    VL - 40

    SP - 2098

    EP - 2103

    JO - Stroke

    JF - Stroke

    SN - 0039-2499

    IS - 6

    ER -

    Sare G, Ali M, Shuaib A, Bath PMW. Relationship between hyperacute blood pressure and outcome after ischemic stroke. Stroke. 2009 Jun;40(6):2098-2103. https://doi.org/10.1161/¿STROKEAHA.108.539155

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