Relationship between hyperacute blood pressure and outcome after ischemic stroke

Gillian Sare, Myzoon Ali, Ashfaq Shuaib, Philip M. W. Bath

    Research output: Contribution to journalArticlepeer-review

    87 Citations (Scopus)


    High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period. Analyses included 1722 patients in hyperacute trials (recruitment <8 hours) from the Virtual Stroke International Stroke Trial Archive (VISTA) Collaboration. Data on BP at enrolment and after 1, 2, 16, 24, 48, and 72 hours, neurological impairment at 7 days (NIHSS), and functional outcome at 90 days (modified Rankin scale) were assessed using logistic regression models, adjusted for confounding variables; results are for 10-mm Hg change in BP.
    Original languageEnglish
    Pages (from-to)2098-2103
    Number of pages6
    Issue number6
    Early online date9 Apr 2009
    Publication statusPublished - Jun 2009


    • stroke
    • high blood pressure
    • ischemic stroke


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