Ranking predictors of sustained viral response for chronic hepatitis C patients treated with pegylated interferon and ribavirin in Scotland

Hamish Innes, Sharon Hutchinson, Samual Allen, Diptendu Bhattacharyya, Peter Bramley, B. Carman, Toby E.S. Delahooke, John F. Dillon, David J. Goldberg, Nicholas Kennedy, Peter R. Mills, John Morris, Judith Morris, Chris Robertson, Adrian J. Stanley, Peter Hayes

Research output: Contribution to journalArticle

Abstract

From the literature on the hepatitis C virus, the existence of a gap between a sustained virologic response (SVR) attainable in randomized clinical trials (RCTs) versus routine practice is not clear. Further, in terms of the pretreatment prediction of SVR, to date, studies have focused only on reporting the magnitude of association (MOA) between each predictor and an SVR. They fail to acknowledge that a predictor with a large MOA is of little value to clinicians if it has low variability in the treatment population.
Original languageEnglish
Pages (from-to)646–655
Number of pages10
JournalEuropean Journal of Gastroenterology and Hepatology
Volume24
Issue number6
DOIs
Publication statusPublished - 2012

Keywords

  • hepatitis C

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