Proficiency test of non-target screening with gas chromatography mass spectrometry to confirm a detected contamination of raw and drinking water

Michael Petri, JiaQian Jiang, Matthias Maier

Research output: Contribution to journalArticle

Abstract

Much of the water supply industry has implemented online monitoring and warning systems for chemical or biological contaminations. When a contamination is detected, further investigations are necessary to confirm or to cancel the initial alarm. The proficiency of a non-target screening approach with solid phase extraction and GCMS in full-scan mode was examined. A selection of pesticides and industry chemicals was used for proficiency testing in extracts of raw and drinking water from Lake Constance. All total ion chromatograms (TIC) of extracted water samples showed a significant chemical background that have an adverse effect on compound identification. The TIC was evaluated with a two-dimensional search algorithm considering mass spectra similarity and retention index for identification, which was used an additional identification criteria to increase the confidence in identification. At a spiking level of 0.50mg/l, up to 70% of the pollutants were unambiguously assignable. The sample pre-treatment was kept as simple as possible to reduce analysing time. A solid-phase extraction with extraction disks at flow rates up to 100 ml/min without any precedent filtration step reduces the sample pre-treatment time for a 1 l-sample below one hour. The recovery rates for most of the examined pollutants were above 60%.

Original languageEnglish
Pages (from-to)805-813
Number of pages9
JournalWater Science and Technology: Water Supply
Volume10
Issue number5
DOIs
Publication statusPublished - 1 Oct 2010

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gas chromatography
mass spectrometry
drinking water
warning system
ion
pollutant
chemical industry
monitoring system
water supply
pesticide
industry
lake
test
raw water
screening
contamination
water
rate
alarm
biological contamination

Keywords

  • gas chromatography
  • mass spectrometry
  • contamination warning system

Cite this

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title = "Proficiency test of non-target screening with gas chromatography mass spectrometry to confirm a detected contamination of raw and drinking water",
abstract = "Much of the water supply industry has implemented online monitoring and warning systems for chemical or biological contaminations. When a contamination is detected, further investigations are necessary to confirm or to cancel the initial alarm. The proficiency of a non-target screening approach with solid phase extraction and GCMS in full-scan mode was examined. A selection of pesticides and industry chemicals was used for proficiency testing in extracts of raw and drinking water from Lake Constance. All total ion chromatograms (TIC) of extracted water samples showed a significant chemical background that have an adverse effect on compound identification. The TIC was evaluated with a two-dimensional search algorithm considering mass spectra similarity and retention index for identification, which was used an additional identification criteria to increase the confidence in identification. At a spiking level of 0.50mg/l, up to 70{\%} of the pollutants were unambiguously assignable. The sample pre-treatment was kept as simple as possible to reduce analysing time. A solid-phase extraction with extraction disks at flow rates up to 100 ml/min without any precedent filtration step reduces the sample pre-treatment time for a 1 l-sample below one hour. The recovery rates for most of the examined pollutants were above 60{\%}.",
keywords = "gas chromatography, mass spectrometry, contamination warning system",
author = "Michael Petri and JiaQian Jiang and Matthias Maier",
note = "Originally published in: Water Science and Technology: Water Supply (2010), 10 (5), pp.805-813.",
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T1 - Proficiency test of non-target screening with gas chromatography mass spectrometry to confirm a detected contamination of raw and drinking water

AU - Petri, Michael

AU - Jiang, JiaQian

AU - Maier, Matthias

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N2 - Much of the water supply industry has implemented online monitoring and warning systems for chemical or biological contaminations. When a contamination is detected, further investigations are necessary to confirm or to cancel the initial alarm. The proficiency of a non-target screening approach with solid phase extraction and GCMS in full-scan mode was examined. A selection of pesticides and industry chemicals was used for proficiency testing in extracts of raw and drinking water from Lake Constance. All total ion chromatograms (TIC) of extracted water samples showed a significant chemical background that have an adverse effect on compound identification. The TIC was evaluated with a two-dimensional search algorithm considering mass spectra similarity and retention index for identification, which was used an additional identification criteria to increase the confidence in identification. At a spiking level of 0.50mg/l, up to 70% of the pollutants were unambiguously assignable. The sample pre-treatment was kept as simple as possible to reduce analysing time. A solid-phase extraction with extraction disks at flow rates up to 100 ml/min without any precedent filtration step reduces the sample pre-treatment time for a 1 l-sample below one hour. The recovery rates for most of the examined pollutants were above 60%.

AB - Much of the water supply industry has implemented online monitoring and warning systems for chemical or biological contaminations. When a contamination is detected, further investigations are necessary to confirm or to cancel the initial alarm. The proficiency of a non-target screening approach with solid phase extraction and GCMS in full-scan mode was examined. A selection of pesticides and industry chemicals was used for proficiency testing in extracts of raw and drinking water from Lake Constance. All total ion chromatograms (TIC) of extracted water samples showed a significant chemical background that have an adverse effect on compound identification. The TIC was evaluated with a two-dimensional search algorithm considering mass spectra similarity and retention index for identification, which was used an additional identification criteria to increase the confidence in identification. At a spiking level of 0.50mg/l, up to 70% of the pollutants were unambiguously assignable. The sample pre-treatment was kept as simple as possible to reduce analysing time. A solid-phase extraction with extraction disks at flow rates up to 100 ml/min without any precedent filtration step reduces the sample pre-treatment time for a 1 l-sample below one hour. The recovery rates for most of the examined pollutants were above 60%.

KW - gas chromatography

KW - mass spectrometry

KW - contamination warning system

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DO - 10.2166/ws.2010.191

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SN - 1606-9749

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