Prevalence and incidence of affective disorders and related factors: observational study

Sally-Ann Cooper, Elita Smiley, Linda Allan, Alison Jackson, Janet Finlayson, Dipali Mantry, Jillian Morrison

Research output: Contribution to journalMeeting abstractpeer-review


Aims: To determine point prevalence and incidence of affective disorders, and factors associated with depression.
Methods: Prospective cohort study; general community setting. All adults (¿¿ years+) with intellectual disabilities, in a defined area. Individual assessments.
Results: 1023 participated (65.5¿%); 651 over 2 years Point prevalence of DC-LD depression was 3.8 % (95%CI = 2.7 - 5.2), mania 0.6 %(95 %CI = 0.2-1.3). Additionally, 1.0 % had bipolar disorder in remission, and 0.1 % first episode mania in remission. Two year incidence of DC-LD depression was 6.6 %, mania 1.1 %, first episode mania 0.3 ¿%.Standardized incidence ratio for depression = 1.07 (95 %CI = 0.76 –148); first episode mania = 1.07 (95 %CI = 5.0 –149.8). Depression was associated with female gender, smoking, number of GP appointments,and preceding life events. Unlike general population findings, not having day-time occupation was not independently associated; nor was previous long-stay hospital residence, severity of intellectual disabilities, or sensory impairments. Conclusions: Adults with intellectual disabilities have a high point prevalence of affective disorders, particularly mania.Associated factors differ from general population findings. Understanding this is important in order to develop appropriate interventions, public strategy, and policy, to reduce existing health inequalities.
Original languageEnglish
Pages (from-to)725
Number of pages1
JournalJournal of Intellectual Disability Research
Publication statusPublished - Aug 2008


  • intellectual disabilities
  • affective disorder
  • gender differences
  • patient studies
  • smoking


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