Prevalence and incidence of affective disorders and related factors: observational study

Sally-Ann Cooper; Elita Smiley; Linda Allan; Alison Jackson; Janet Finlayson; Dipali Mantry; Jillian Morrison

doi:10.1111/j.1365-2788.2008.01090.x

Abstract

Aims: To determine point prevalence and incidence of affective disorders, and factors associated with depression.
Methods: Prospective cohort study; general community setting. All adults (¿¿ years+) with intellectual disabilities, in a defined area. Individual assessments.
Results: 1023 participated (65.5¿%); 651 over 2 years Point prevalence of DC-LD depression was 3.8 % (95%CI = 2.7 - 5.2), mania 0.6 %(95 %CI = 0.2-1.3). Additionally, 1.0 % had bipolar disorder in remission, and 0.1 % first episode mania in remission. Two year incidence of DC-LD depression was 6.6 %, mania 1.1 %, first episode mania 0.3 ¿%.Standardized incidence ratio for depression = 1.07 (95 %CI = 0.76 –148); first episode mania = 1.07 (95 %CI = 5.0 –149.8). Depression was associated with female gender, smoking, number of GP appointments,and preceding life events. Unlike general population findings, not having day-time occupation was not independently associated; nor was previous long-stay hospital residence, severity of intellectual disabilities, or sensory impairments. Conclusions: Adults with intellectual disabilities have a high point prevalence of affective disorders, particularly mania.Associated factors differ from general population findings. Understanding this is important in order to develop appropriate interventions, public strategy, and policy, to reduce existing health inequalities.

Original language	English
Pages (from-to)	725
Number of pages	1
Journal	Journal of Intellectual Disability Research
Volume	52
DOIs	https://doi.org/10.1111/j.1365-2788.2008.01090.x
Publication status	Published - Aug 2008

Keywords

intellectual disabilities
affective disorder
gender differences
patient studies
smoking

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Documents and Links

10.1111/j.1365-2788.2008.01090.x

Cite this

@article{6a75ae036234444b83203132d2f4d546,

title = "Prevalence and incidence of affective disorders and related factors: observational study",

abstract = "Aims: To determine point prevalence and incidence of affective disorders, and factors associated with depression. Methods: Prospective cohort study; general community setting. All adults (¿¿ years+) with intellectual disabilities, in a defined area. Individual assessments.Results: 1023 participated (65.5¿%); 651 over 2 years Point prevalence of DC-LD depression was 3.8 % (95%CI = 2.7 - 5.2), mania 0.6 %(95 %CI = 0.2-1.3). Additionally, 1.0 % had bipolar disorder in remission, and 0.1 % first episode mania in remission. Two year incidence of DC-LD depression was 6.6 %, mania 1.1 %, first episode mania 0.3 ¿%.Standardized incidence ratio for depression = 1.07 (95 %CI = 0.76 –148); first episode mania = 1.07 (95 %CI = 5.0 –149.8). Depression was associated with female gender, smoking, number of GP appointments,and preceding life events. Unlike general population findings, not having day-time occupation was not independently associated; nor was previous long-stay hospital residence, severity of intellectual disabilities, or sensory impairments. Conclusions: Adults with intellectual disabilities have a high point prevalence of affective disorders, particularly mania.Associated factors differ from general population findings. Understanding this is important in order to develop appropriate interventions, public strategy, and policy, to reduce existing health inequalities.",

keywords = "intellectual disabilities, affective disorder, gender differences, patient studies, smoking",

author = "Sally-Ann Cooper and Elita Smiley and Linda Allan and Alison Jackson and Janet Finlayson and Dipali Mantry and Jillian Morrison",

note = "From checking journal, this is an abstract. Changed template over from journal article. ET 4-10-13",

year = "2008",

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doi = "10.1111/j.1365-2788.2008.01090.x",

language = "English",

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journal = "Journal of Intellectual Disability Research",

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TY - JOUR

T1 - Prevalence and incidence of affective disorders and related factors: observational study

AU - Cooper, Sally-Ann

AU - Smiley, Elita

AU - Allan, Linda

AU - Jackson, Alison

AU - Finlayson, Janet

AU - Mantry, Dipali

AU - Morrison, Jillian

N1 - From checking journal, this is an abstract. Changed template over from journal article. ET 4-10-13

PY - 2008/8

Y1 - 2008/8

N2 - Aims: To determine point prevalence and incidence of affective disorders, and factors associated with depression. Methods: Prospective cohort study; general community setting. All adults (¿¿ years+) with intellectual disabilities, in a defined area. Individual assessments.Results: 1023 participated (65.5¿%); 651 over 2 years Point prevalence of DC-LD depression was 3.8 % (95%CI = 2.7 - 5.2), mania 0.6 %(95 %CI = 0.2-1.3). Additionally, 1.0 % had bipolar disorder in remission, and 0.1 % first episode mania in remission. Two year incidence of DC-LD depression was 6.6 %, mania 1.1 %, first episode mania 0.3 ¿%.Standardized incidence ratio for depression = 1.07 (95 %CI = 0.76 –148); first episode mania = 1.07 (95 %CI = 5.0 –149.8). Depression was associated with female gender, smoking, number of GP appointments,and preceding life events. Unlike general population findings, not having day-time occupation was not independently associated; nor was previous long-stay hospital residence, severity of intellectual disabilities, or sensory impairments. Conclusions: Adults with intellectual disabilities have a high point prevalence of affective disorders, particularly mania.Associated factors differ from general population findings. Understanding this is important in order to develop appropriate interventions, public strategy, and policy, to reduce existing health inequalities.

AB - Aims: To determine point prevalence and incidence of affective disorders, and factors associated with depression. Methods: Prospective cohort study; general community setting. All adults (¿¿ years+) with intellectual disabilities, in a defined area. Individual assessments.Results: 1023 participated (65.5¿%); 651 over 2 years Point prevalence of DC-LD depression was 3.8 % (95%CI = 2.7 - 5.2), mania 0.6 %(95 %CI = 0.2-1.3). Additionally, 1.0 % had bipolar disorder in remission, and 0.1 % first episode mania in remission. Two year incidence of DC-LD depression was 6.6 %, mania 1.1 %, first episode mania 0.3 ¿%.Standardized incidence ratio for depression = 1.07 (95 %CI = 0.76 –148); first episode mania = 1.07 (95 %CI = 5.0 –149.8). Depression was associated with female gender, smoking, number of GP appointments,and preceding life events. Unlike general population findings, not having day-time occupation was not independently associated; nor was previous long-stay hospital residence, severity of intellectual disabilities, or sensory impairments. Conclusions: Adults with intellectual disabilities have a high point prevalence of affective disorders, particularly mania.Associated factors differ from general population findings. Understanding this is important in order to develop appropriate interventions, public strategy, and policy, to reduce existing health inequalities.

KW - intellectual disabilities

KW - affective disorder

KW - gender differences

KW - patient studies

KW - smoking

U2 - 10.1111/j.1365-2788.2008.01090.x

DO - 10.1111/j.1365-2788.2008.01090.x

M3 - Meeting abstract

SN - 1365-2788

VL - 52

SP - 725

JO - Journal of Intellectual Disability Research

JF - Journal of Intellectual Disability Research

ER -