Abstract
BACKGROUND: Our current knowledge about predictors of admission and re-admission to hospital as a result of major depressive disorder (MDD) is limited. Here we present a descriptive analysis of factors which are associated with MDD hospitalisations within a large population cohort.
METHODS:
We linked participants of the Scottish Health Survey (SHS) to historical and prospective hospital admission data. We combined information from the SHS baseline interview and historical hospitalisations to define a range of exposure variables. The main outcomes of interest were: (1) first time admission for MDD occurring after the SHS interview; and (2) readmission for MDD. We used Cox regression to determine the association between each predictor and each outcome, after adjusting for age, gender and deprivation quintile.
RESULTS:
52,990 adult SHS participants were included. During a median follow-up of 4.5 years per participant, we observed 530 first-time admissions for MDD. A relatively wide range of factors - encompassing social, individual health status, and lifestyle-related exposures - were associated with this outcome (p<0.05). Among the 530 participants exhibiting a de novo admission for MDD during follow-up, 118 were later re-admitted. Only older age (over 70) and a prior non-depression related psychiatric admission were associated with readmission for MDD.
LIMTATIONS:
MDD was defined using records of International Classification of Disease hospital discharge codes rather than formal diagnostic assessments.
CONCLUSION:
These findings have implications for mental health service organisation and delivery and should stimulate future research on predictive factors for admission and readmission in MDD.
METHODS:
We linked participants of the Scottish Health Survey (SHS) to historical and prospective hospital admission data. We combined information from the SHS baseline interview and historical hospitalisations to define a range of exposure variables. The main outcomes of interest were: (1) first time admission for MDD occurring after the SHS interview; and (2) readmission for MDD. We used Cox regression to determine the association between each predictor and each outcome, after adjusting for age, gender and deprivation quintile.
RESULTS:
52,990 adult SHS participants were included. During a median follow-up of 4.5 years per participant, we observed 530 first-time admissions for MDD. A relatively wide range of factors - encompassing social, individual health status, and lifestyle-related exposures - were associated with this outcome (p<0.05). Among the 530 participants exhibiting a de novo admission for MDD during follow-up, 118 were later re-admitted. Only older age (over 70) and a prior non-depression related psychiatric admission were associated with readmission for MDD.
LIMTATIONS:
MDD was defined using records of International Classification of Disease hospital discharge codes rather than formal diagnostic assessments.
CONCLUSION:
These findings have implications for mental health service organisation and delivery and should stimulate future research on predictive factors for admission and readmission in MDD.
| Original language | English |
|---|---|
| Pages (from-to) | 10-14 |
| Number of pages | 5 |
| Journal | Journal of Affective Disorders |
| Volume | 183 |
| Early online date | 23 Apr 2015 |
| DOIs | |
| Publication status | Published - 1 Sept 2015 |
Keywords
- depression
- predictors
Documents and Links
- Innes, H. et al (2015) Predictors of admission and readmission to hospital for major depression: a community cohort study of 52,990 individuals
This is the author accepted author version of an article published in Journal of Affective Disorders by Elsevier. Available at: http://www.jad-journal.com/article/S0165-0327(15)00234-7/fulltext Copyright: © 2015 Elsevier B.V. Published by Elsevier Inc. All rights reserved.