Patient-important benefits of clearing the hepatitis C virus through treatment: a simulation model

Hamish Innes, David Goldberg, Geoffrey Dusheiko, Peter Hayes, Peter R. Mills, John F. Dillon, Esther Aspinall, Stephen T. Barclay, Sharon J. Hutchinson

Research output: Contribution to journalArticle

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Abstract

Given an appreciable risk of adverse-effects, current therapies for chronic hepatitis C virus (HCV) infection pose a dilemma to patients. We explored, via simulation modelling, patient-important benefits of attaining a sustained viral response (SVR).
Original languageEnglish
Pages (from-to)1118-1126
Number of pages9
JournalJournal of Hepatology
Volume60
Issue number6
Early online date6 Feb 2014
DOIs
Publication statusPublished - Jun 2014

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Patient Simulation
Chronic Hepatitis C
Virus Diseases
Hepacivirus
Therapeutics

Keywords

  • Hepatitis C virus
  • sustained viral response
  • HCV
  • liver disease

Cite this

Innes, H., Goldberg, D., Dusheiko, G., Hayes, P., Mills, P. R., Dillon, J. F., ... Hutchinson, S. J. (2014). Patient-important benefits of clearing the hepatitis C virus through treatment: a simulation model. Journal of Hepatology, 60 (6), 1118-1126. https://doi.org/10.1016/j.jhep.2014.01.020
Innes, Hamish ; Goldberg, David ; Dusheiko, Geoffrey ; Hayes, Peter ; Mills, Peter R. ; Dillon, John F. ; Aspinall, Esther ; Barclay, Stephen T. ; Hutchinson, Sharon J. / Patient-important benefits of clearing the hepatitis C virus through treatment : a simulation model. In: Journal of Hepatology. 2014 ; Vol. 60 , No. 6. pp. 1118-1126.
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keywords = "Hepatitis C virus , sustained viral response, HCV, liver disease",
author = "Hamish Innes and David Goldberg and Geoffrey Dusheiko and Peter Hayes and Mills, {Peter R.} and Dillon, {John F.} and Esther Aspinall and Barclay, {Stephen T.} and Hutchinson, {Sharon J.}",
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Innes, H, Goldberg, D, Dusheiko, G, Hayes, P, Mills, PR, Dillon, JF, Aspinall, E, Barclay, ST & Hutchinson, SJ 2014, 'Patient-important benefits of clearing the hepatitis C virus through treatment: a simulation model', Journal of Hepatology, vol. 60 , no. 6, pp. 1118-1126. https://doi.org/10.1016/j.jhep.2014.01.020

Patient-important benefits of clearing the hepatitis C virus through treatment : a simulation model. / Innes, Hamish; Goldberg, David; Dusheiko, Geoffrey; Hayes, Peter ; Mills, Peter R.; Dillon, John F.; Aspinall, Esther; Barclay, Stephen T.; Hutchinson, Sharon J.

In: Journal of Hepatology, Vol. 60 , No. 6, 06.2014, p. 1118-1126.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Patient-important benefits of clearing the hepatitis C virus through treatment

T2 - a simulation model

AU - Innes, Hamish

AU - Goldberg, David

AU - Dusheiko, Geoffrey

AU - Hayes, Peter

AU - Mills, Peter R.

AU - Dillon, John F.

AU - Aspinall, Esther

AU - Barclay, Stephen T.

AU - Hutchinson, Sharon J.

N1 - Date of acceptance: 27/01/2014

PY - 2014/6

Y1 - 2014/6

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AB - Given an appreciable risk of adverse-effects, current therapies for chronic hepatitis C virus (HCV) infection pose a dilemma to patients. We explored, via simulation modelling, patient-important benefits of attaining a sustained viral response (SVR).

KW - Hepatitis C virus

KW - sustained viral response

KW - HCV

KW - liver disease

U2 - 10.1016/j.jhep.2014.01.020

DO - 10.1016/j.jhep.2014.01.020

M3 - Article

VL - 60

SP - 1118

EP - 1126

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Innes H, Goldberg D, Dusheiko G, Hayes P, Mills PR, Dillon JF et al. Patient-important benefits of clearing the hepatitis C virus through treatment: a simulation model. Journal of Hepatology. 2014 Jun;60 (6):1118-1126. https://doi.org/10.1016/j.jhep.2014.01.020