Neonatal visual evoked potentials in infants born to mothers prescribed methadone

Laura McGlone, Ruth Hamilton, Daphne L. McCulloch, Richard Bolton, Michael S. Bradnam, Lawrence T. Weaver, Helen Mactier

Research output: Contribution to journalArticle

Abstract

Drug misuse in pregnancy is associated with impaired infant visual development. Pilot data showed abnormal flash visual evoked potentials (VEPs) in neonates exposed to methadone in utero, but results were confounded by intrauterine growth restriction, gestation, and ongoing drug misuse. This large cohort study aimed to clarify the effects on neonatal flash VEPs of maternal drug misuse in pregnancy, including prescription of substitute methadone and subsequent development of neonatal abstinence syndrome.
Original languageEnglish
Pages (from-to)e857-e863
Number of pages7
JournalPediatrics
Volume131
Issue number3
Early online date18 Feb 2013
DOIs
Publication statusPublished - Mar 2013

Fingerprint

Visual Evoked Potentials
Methadone
Mothers
Pregnancy
Neonatal Abstinence Syndrome
Pharmaceutical Preparations
Child Development
Prescriptions
Cohort Studies
Newborn Infant
Growth

Keywords

  • drug misuse
  • pregnancy
  • visual development
  • neonates
  • methadone

Cite this

McGlone, L., Hamilton, R., McCulloch, D. L., Bolton, R., Bradnam, M. S., Weaver, L. T., & Mactier, H. (2013). Neonatal visual evoked potentials in infants born to mothers prescribed methadone. Pediatrics, 131(3), e857-e863. https://doi.org/10.1542/peds.2012-2113
McGlone, Laura ; Hamilton, Ruth ; McCulloch, Daphne L. ; Bolton, Richard ; Bradnam, Michael S. ; Weaver, Lawrence T. ; Mactier, Helen. / Neonatal visual evoked potentials in infants born to mothers prescribed methadone. In: Pediatrics. 2013 ; Vol. 131, No. 3. pp. e857-e863.
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McGlone, L, Hamilton, R, McCulloch, DL, Bolton, R, Bradnam, MS, Weaver, LT & Mactier, H 2013, 'Neonatal visual evoked potentials in infants born to mothers prescribed methadone', Pediatrics, vol. 131, no. 3, pp. e857-e863. https://doi.org/10.1542/peds.2012-2113

Neonatal visual evoked potentials in infants born to mothers prescribed methadone. / McGlone, Laura; Hamilton, Ruth; McCulloch, Daphne L.; Bolton, Richard; Bradnam, Michael S.; Weaver, Lawrence T.; Mactier, Helen.

In: Pediatrics, Vol. 131, No. 3, 03.2013, p. e857-e863.

Research output: Contribution to journalArticle

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McGlone L, Hamilton R, McCulloch DL, Bolton R, Bradnam MS, Weaver LT et al. Neonatal visual evoked potentials in infants born to mothers prescribed methadone. Pediatrics. 2013 Mar;131(3):e857-e863. https://doi.org/10.1542/peds.2012-2113