Drug misuse in pregnancy is associated with impaired infant visual development. Pilot data showed abnormal flash visual evoked potentials (VEPs) in neonates exposed to methadone in utero, but results were confounded by intrauterine growth restriction, gestation, and ongoing drug misuse. This large cohort study aimed to clarify the effects on neonatal flash VEPs of maternal drug misuse in pregnancy, including prescription of substitute methadone and subsequent development of neonatal abstinence syndrome.
- drug misuse
- visual development
McGlone, L., Hamilton, R., McCulloch, D. L., Bolton, R., Bradnam, M. S., Weaver, L. T., & Mactier, H. (2013). Neonatal visual evoked potentials in infants born to mothers prescribed methadone. Pediatrics, 131(3), e857-e863. https://doi.org/10.1542/peds.2012-2113