Neonatal visual evoked potentials in infants born to mothers prescribed methadone

Laura McGlone, Ruth Hamilton, Daphne L. McCulloch, Richard Bolton, Michael S. Bradnam, Lawrence T. Weaver, Helen Mactier

Research output: Contribution to journalArticle

Abstract

Drug misuse in pregnancy is associated with impaired infant visual development. Pilot data showed abnormal flash visual evoked potentials (VEPs) in neonates exposed to methadone in utero, but results were confounded by intrauterine growth restriction, gestation, and ongoing drug misuse. This large cohort study aimed to clarify the effects on neonatal flash VEPs of maternal drug misuse in pregnancy, including prescription of substitute methadone and subsequent development of neonatal abstinence syndrome.
Original languageEnglish
Pages (from-to)e857-e863
Number of pages7
JournalPediatrics
Volume131
Issue number3
Early online date18 Feb 2013
DOIs
Publication statusPublished - Mar 2013

Keywords

  • drug misuse
  • pregnancy
  • visual development
  • neonates
  • methadone

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    McGlone, L., Hamilton, R., McCulloch, D. L., Bolton, R., Bradnam, M. S., Weaver, L. T., & Mactier, H. (2013). Neonatal visual evoked potentials in infants born to mothers prescribed methadone. Pediatrics, 131(3), e857-e863. https://doi.org/10.1542/peds.2012-2113