[Mo(TmMe)(O)2Cl]: An alternative functional model of sulfite oxidase: An alternative functional model of sulfite oxidase

Dawn Wallace; Lorraine T. Gibson; John Reglinski; Mark D. Spicer

doi:10.1021/ic700468m

[Mo(Tm^Me)(O)₂Cl]: An alternative functional model of sulfite oxidase: An alternative functional model of sulfite oxidase

Dawn Wallace^*, Lorraine T. Gibson, John Reglinski, Mark D. Spicer

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

The hydrotris(methimazolyl)borate anion (Tm^Me) has been used to synthesize an alternative functional model ([Mo(Tm^Me)(O) ₂Cl]) of the metalloenzyme sulfite oxidase. It has been shown that the complex undergoes oxygen atom transfer chemistry and that it performs the primary function of the enzyme, sulfite oxidation. A method using ion chromatography has been developed to definitively prove that sulfite is oxidized to sulfate. Employment of a soft tripodal ligand has allowed us to tune the redox potentials of our complex so that they are significantly closer to those reported for sulfite oxidase.

Original language	English
Pages (from-to)	3804-3806
Number of pages	3
Journal	Inorganic Chemistry
Volume	46
Issue number	10
Early online date	10 Apr 2007
DOIs	https://doi.org/10.1021/ic700468m
Publication status	Published - 1 May 2007
Externally published	Yes

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Inorganic Chemistry

Documents and Links

10.1021/ic700468m

Cite this

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abstract = "The hydrotris(methimazolyl)borate anion (TmMe) has been used to synthesize an alternative functional model ([Mo(TmMe)(O) 2Cl]) of the metalloenzyme sulfite oxidase. It has been shown that the complex undergoes oxygen atom transfer chemistry and that it performs the primary function of the enzyme, sulfite oxidation. A method using ion chromatography has been developed to definitively prove that sulfite is oxidized to sulfate. Employment of a soft tripodal ligand has allowed us to tune the redox potentials of our complex so that they are significantly closer to those reported for sulfite oxidase.",

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AU - Gibson, Lorraine T.

AU - Reglinski, John

AU - Spicer, Mark D.

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N2 - The hydrotris(methimazolyl)borate anion (TmMe) has been used to synthesize an alternative functional model ([Mo(TmMe)(O) 2Cl]) of the metalloenzyme sulfite oxidase. It has been shown that the complex undergoes oxygen atom transfer chemistry and that it performs the primary function of the enzyme, sulfite oxidation. A method using ion chromatography has been developed to definitively prove that sulfite is oxidized to sulfate. Employment of a soft tripodal ligand has allowed us to tune the redox potentials of our complex so that they are significantly closer to those reported for sulfite oxidase.

AB - The hydrotris(methimazolyl)borate anion (TmMe) has been used to synthesize an alternative functional model ([Mo(TmMe)(O) 2Cl]) of the metalloenzyme sulfite oxidase. It has been shown that the complex undergoes oxygen atom transfer chemistry and that it performs the primary function of the enzyme, sulfite oxidation. A method using ion chromatography has been developed to definitively prove that sulfite is oxidized to sulfate. Employment of a soft tripodal ligand has allowed us to tune the redox potentials of our complex so that they are significantly closer to those reported for sulfite oxidase.

U2 - 10.1021/ic700468m

DO - 10.1021/ic700468m

M3 - Article

AN - SCOPUS:34249687503

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JO - Inorganic Chemistry

JF - Inorganic Chemistry

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