Modelling contralesional movement slowing after unilateral brain damage

Casimir J.H.  Ludwig; Stephen H Butler; Stephanie Rossit; Monika Harvey; Iain D.  Gilchrist

doi:10.1016/j.neulet.2009.01.033

Modelling contralesional movement slowing after unilateral brain damage

Casimir J.H. Ludwig, Stephen H Butler, Stephanie Rossit, Monika Harvey, Iain D. Gilchrist

Research output: Contribution to journal › Article › peer-review

Abstract

Effective interaction with the world requires the brain to signal behaviourally relevant events and organise an appropriate and timely motor response to such events. Unilateral brain lesion typically results in a reduction and slowing of motor behaviour directed to contralesional space. Accumulator models of choice and reaction time can distinguish between two possible functional causes of this deficit: slowed extraction of evidence in favour of a motor response or an increase in the required amount of evidence for response generation. Three patients with unilateral damage to the right hemisphere were tested on a visually guided saccade task.

Original language	English
Pages (from-to)	1-4
Number of pages	4
Journal	Neuroscience Letters
Volume	452
Issue number	1
DOIs	https://doi.org/10.1016/j.neulet.2009.01.033
Publication status	Published - Mar 2009

Keywords

brain lesion
neuropsychology
computational modelling
motor response

Documents and Links

10.1016/j.neulet.2009.01.033

http://www.sciencedirect.com/science/article/pii/S0304394009000615

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abstract = "Effective interaction with the world requires the brain to signal behaviourally relevant events and organise an appropriate and timely motor response to such events. Unilateral brain lesion typically results in a reduction and slowing of motor behaviour directed to contralesional space. Accumulator models of choice and reaction time can distinguish between two possible functional causes of this deficit: slowed extraction of evidence in favour of a motor response or an increase in the required amount of evidence for response generation. Three patients with unilateral damage to the right hemisphere were tested on a visually guided saccade task. ",

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KW - neuropsychology

KW - computational modelling

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