Abstract
MIDA boronates are among the most useful reagents for the Suzuki–Miyaura reaction. This chemistry typically generates new bonds between two aromatic rings, thereby restricting access to important areas of chemical space. Here we demonstrate the coupling of MIDA boronates to allylic electrophiles, including a new synthesis of the well-known COX inhibitor ibuprofen.
Original language | English |
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Pages (from-to) | 30624-30630 |
Number of pages | 7 |
Journal | RSC Advances |
Volume | 10 |
Issue number | 51 |
DOIs | |
Publication status | Published - 18 Aug 2020 |
Externally published | Yes |
Keywords
- MIDA boronates
- allylic electrophiles
- COX inhibitor ibruprofen
ASJC Scopus subject areas
- General Chemical Engineering
- General Chemistry