Microbial safety in xenotransplantation

Mueller  Nicolas J.; Takeuchi Yasuhiro; Mattiuzzo Giada; Linda Scobie

doi:10.1097/MOT.0b013e32834486f6

Microbial safety in xenotransplantation

Mueller Nicolas J., Takeuchi Yasuhiro, Mattiuzzo Giada, Linda Scobie

Biological and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

Abstract

As clinical trials are in progress involving porcine islet cell transplantation, microbial safety remains a key issue. Therefore, in the context of pig-to-human xenotransplantation, we provide an overview of the recent progress in the studies of relevant viruses including well known problematic viruses, such as herpesviruses and porcine endogenous retroviruses (PERV) in addition to some emerging issues regarding other pathogens.

Original language	English
Pages (from-to)	201-206
Number of pages	6
Journal	Current Opinion in Organ Transplantation
Volume	16
Issue number	2
DOIs	https://doi.org/10.1097/MOT.0b013e32834486f6
Publication status	Published - Apr 2011

Keywords

xenotransplantation
porcine endogenous retroviruses
pathogens
porcine cell biology

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10.1097/MOT.0b013e32834486f6

Cite this

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title = "Microbial safety in xenotransplantation",

abstract = "As clinical trials are in progress involving porcine islet cell transplantation, microbial safety remains a key issue. Therefore, in the context of pig-to-human xenotransplantation, we provide an overview of the recent progress in the studies of relevant viruses including well known problematic viruses, such as herpesviruses and porcine endogenous retroviruses (PERV) in addition to some emerging issues regarding other pathogens.",

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author = "{Nicolas J.}, Mueller and Takeuchi Yasuhiro and Mattiuzzo Giada and Linda Scobie",

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AU - Nicolas J., Mueller

AU - Yasuhiro, Takeuchi

AU - Giada, Mattiuzzo

AU - Scobie, Linda

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AB - As clinical trials are in progress involving porcine islet cell transplantation, microbial safety remains a key issue. Therefore, in the context of pig-to-human xenotransplantation, we provide an overview of the recent progress in the studies of relevant viruses including well known problematic viruses, such as herpesviruses and porcine endogenous retroviruses (PERV) in addition to some emerging issues regarding other pathogens.

KW - xenotransplantation

KW - porcine endogenous retroviruses

KW - pathogens

KW - porcine cell biology

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EP - 206

JO - Current Opinion in Organ Transplantation

JF - Current Opinion in Organ Transplantation

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Microbial safety in xenotransplantation

Abstract

Keywords

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