Microbial safety in xenotransplantation

Mueller Nicolas J., Takeuchi Yasuhiro, Mattiuzzo Giada, Linda Scobie

Research output: Contribution to journalArticle

Abstract

As clinical trials are in progress involving porcine islet cell transplantation, microbial safety remains a key issue. Therefore, in the context of pig-to-human xenotransplantation, we provide an overview of the recent progress in the studies of relevant viruses including well known problematic viruses, such as herpesviruses and porcine endogenous retroviruses (PERV) in addition to some emerging issues regarding other pathogens.
Original languageEnglish
Pages (from-to)201-206
Number of pages6
JournalCurrent Opinion in Organ Transplantation
Volume16
Issue number2
DOIs
Publication statusPublished - Apr 2011

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Keywords

  • xenotransplantation
  • porcine endogenous retroviruses
  • pathogens
  • porcine cell biology

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