Light- and dark-adapted electroretinograms (ERGs) and ocular pigmentation: comparison of brown- and blue-eyed cohorts

Abdlsaed Al Abdlseaed, Yvonne McTaggart, Thomas Ramage, Ruth Hamilton, Daphne L. McCulloch

Research output: Contribution to journalArticle


This study characterizes differences in human ERGs based on ocular pigmentation. Light- and dark-adapted luminance-response (LR) series for a-, b- and i-waves and light-adapted oscillatory potentials (OPs) were recorded in 14 healthy volunteers (7 blue-eyed Caucasians; 7 brown-eyed Asians, aged 20–22 years). Amplitude interpolations were by logistic growth (Naka-Rushton), Gaussian or the combined ‘photopic hill’ functions. Implicit times (IT) for dark-adapted a- and b-waves, and for light-adapted a-, b- and i-waves were earlier in the blue-eyed group than in the brown-eyed group across all flash strengths (P <0.05).

Original languageEnglish
Pages (from-to)135-146
Number of pages12
JournalDocumenta Ophthamologia: the Journal of Clinical Electrophysiology and Vision
Issue number2
Publication statusPublished - 1 Jul 2010



  • optometry
  • electroretinograms
  • vision sciences

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