Is there a preference for PET or SPECT brain imaging in diagnosing dementia? The views of people with dementia, carers, and healthy controls

Claire Bamford, Kirsty Olsen, Chris Davison, Nicky Barnett, Jim Lloyd, David Williams, Michael Firbank, Helen Mason, Cam Donaldson, John O'Brien

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Abstract

Positron emission tomography (PET) and single photon emission computed tomography (SPECT) brain imaging are widely used as diagnostic tools for suspected dementia but no studies have directly compared participant views of the two procedures. We used a range of methods to explore preferences for PET and SPECT. Patients and controls (and accompanying carers) completed questionnaires immediately after undergoing PET and SPECT brain scans. Pulse rate data were collected during each scan. Scan attributes were prioritized using a card sorting exercise; carers and controls additionally answered willingness to pay (WTP) questions. Few differences were found either between the scans or groups of participants, although carers marginally preferred SPECT. Diagnostic accuracy was prioritized over other scan characteristics. Mean heart rate during both scans was lower than baseline heart rate measured at home (p < 0.001). Most participants viewed PET and SPECT scans as roughly equivalent and did not have a preference for either scan. Carer preference for SPECT is likely to reflect their desire to be with the patient (routine practice for SPECT but not for PET), suggesting that they should be able to accompany vulnerable patients throughout imaging procedures wherever possible. Pulse rate data indicated that brain imaging was no more stressful than a home visit (HV) from a researcher. The data do not support the anecdotal view that PET is a more burdensome procedure and the use of PET or SPECT scans in dementia should be based on diagnostic accuracy of the technique.
Original languageEnglish
Pages (from-to)123-131
Number of pages9
JournalInternational Psychogeriatrics
Volume28
Issue number1
Early online date15 Jul 2015
DOIs
Publication statusPublished - Jan 2016

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Single-Photon Emission-Computed Tomography
Neuroimaging
Positron-Emission Tomography
Caregivers
Dementia
Heart Rate
House Calls
Research Personnel
Exercise
Brain

Keywords

  • Alzheimer's disease
  • patient preferences
  • willingness to pay
  • brain imaging
  • PET
  • SPECT

Cite this

Bamford, Claire ; Olsen, Kirsty ; Davison, Chris ; Barnett, Nicky ; Lloyd, Jim ; Williams, David ; Firbank, Michael ; Mason, Helen ; Donaldson, Cam ; O'Brien, John. / Is there a preference for PET or SPECT brain imaging in diagnosing dementia? The views of people with dementia, carers, and healthy controls. In: International Psychogeriatrics. 2016 ; Vol. 28, No. 1. pp. 123-131.
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Is there a preference for PET or SPECT brain imaging in diagnosing dementia? The views of people with dementia, carers, and healthy controls. / Bamford, Claire; Olsen, Kirsty; Davison, Chris; Barnett, Nicky ; Lloyd, Jim; Williams, David; Firbank, Michael; Mason, Helen; Donaldson, Cam; O'Brien, John.

In: International Psychogeriatrics, Vol. 28, No. 1, 01.2016, p. 123-131.

Research output: Contribution to journalArticle

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