Abstract
Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone and major component of the enteroinsular axis. Its therapeutic potential in human diabetes is limited by rapid degradation and inactivation by the enzyme dipeptidylpeptidase-4 (DPP-4). We investigated the acute effects of metformin with and without food on DPP-4 activity in Type 2 diabetes.
Original language | English |
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Pages (from-to) | 649-654 |
Number of pages | 6 |
Journal | Diabetic Medicine |
Volume | 26 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2009 |
Keywords
- type 2 diabetes
- insulin
- metformin