Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 649-654 |
| Number of pages | 6 |
| Journal | Diabetic Medicine |
| Volume | 26 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2009 |
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Keywords
- type 2 diabetes
- insulin
- metformin
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Investigation of the effect of oral metformin on dipeptidylpeptidase-4 (DPP-4) activity in Type 2 diabetes. / Cuthberston, Joy; Patterson, Steven; O'Harte, Finbarr; Bell, Patrick .
In: Diabetic Medicine, Vol. 26, No. 6, 06.2009, p. 649-654.Research output: Contribution to journal › Article
TY - JOUR
T1 - Investigation of the effect of oral metformin on dipeptidylpeptidase-4 (DPP-4) activity in Type 2 diabetes
AU - Cuthberston, Joy
AU - Patterson, Steven
AU - O'Harte, Finbarr
AU - Bell, Patrick
PY - 2009/6
Y1 - 2009/6
N2 - Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone and major component of the enteroinsular axis. Its therapeutic potential in human diabetes is limited by rapid degradation and inactivation by the enzyme dipeptidylpeptidase-4 (DPP-4). We investigated the acute effects of metformin with and without food on DPP-4 activity in Type 2 diabetes.
AB - Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone and major component of the enteroinsular axis. Its therapeutic potential in human diabetes is limited by rapid degradation and inactivation by the enzyme dipeptidylpeptidase-4 (DPP-4). We investigated the acute effects of metformin with and without food on DPP-4 activity in Type 2 diabetes.
KW - type 2 diabetes
KW - insulin
KW - metformin
U2 - 10.1111/j.1464-5491.2009.02748.x
DO - 10.1111/j.1464-5491.2009.02748.x
M3 - Article
VL - 26
SP - 649
EP - 654
JO - Diabetic Medicine
JF - Diabetic Medicine
SN - 0742-3071
IS - 6
ER -