Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis

Ugo Soffientini, Anna-Maria Caridis, Sharron Dolan, Ann Graham

Research output: Contribution to journalArticle

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Abstract

The aim of this study was to examine hepatic expression of cholesterol-trafficking proteins, mitochondrial StarD1 and endosomal StarD3, and their relationship with dyslipidaemia and steatosis in Zucker (fa/fa) genetically obese rats, and to explore their functional role in lipid metabolism in rat McArdle RH-7777 hepatoma cells.
Original languageEnglish
Pages (from-to)1372-1382
Number of pages11
JournalBiochimica et Biophysica Acta (BBA)
Volume1842
Issue number10
Early online date9 Jul 2014
DOIs
Publication statusPublished - 2014

Fingerprint

Dyslipidemias
Lipid Metabolism
Cholesterol
Liver
Mitochondrial Proteins
Protein Transport
Hepatocellular Carcinoma

Keywords

  • cholesterol
  • hepatic expression
  • proteins
  • lipid metabolism

Cite this

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Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis. / Soffientini, Ugo; Caridis, Anna-Maria; Dolan, Sharron; Graham, Ann.

In: Biochimica et Biophysica Acta (BBA), Vol. 1842, No. 10, 2014, p. 1372-1382.

Research output: Contribution to journalArticle

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T1 - Intracellular cholesterol transporters and modulation of hepatic lipid metabolism: Implications for diabetic dyslipidaemia and steatosis

AU - Soffientini, Ugo

AU - Caridis, Anna-Maria

AU - Dolan, Sharron

AU - Graham, Ann

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KW - hepatic expression

KW - proteins

KW - lipid metabolism

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M3 - Article

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JO - Biochimica et Biophysica Acta (BBA)

JF - Biochimica et Biophysica Acta (BBA)

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