Interventions for disorders of eye movement in patients with stroke

Alex Pollock, Christine Roberta Hazelton, Clair A. Henderson, Jayne Angilley, Baljean Dhillon, Peter Langhorne, Katrina Livingstone, Frank A. Munro, Heather Orr, Fiona J. Rowe, Uma Shahani

Research output: Contribution to journalArticle

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Abstract

Background: Eye movement disorders may affect over 70% of stroke patients. These eye movement disorders can result in difficulty maintaining the normal ocular position and difficulty moving the eyes appropriately. The resulting functional disabilities include a loss of depth perception, reduced hand-to-eye co-ordination, marked difficulties with near tasks and reading and reduced ability to scan the visual environment. They can also impact on the effectiveness of rehabilitation therapy. There are a wide variety of different treatment interventions proposed for eye movement disorders after stroke. However, in the past, there has been a lack of evidence specific to the impact of interventions on the functional outcome of patients with stroke.
Objectives: To determine the effects of interventions for eye movement disorders on functional ability following stroke.
Search methods: We searched the Cochrane Stroke Group Trials Register (February 2011), the Cochrane Eyes and Vision Group Trials Register (December 2009) and nine electronic bibliographic databases including CENTRAL (The Cochrane Library 2009, Issue 4), MEDLINE (1950 to December 2009), EMBASE (1980 to December 2009), CINAHL (1982 to December 2009), AMED (1985 to December 2009), and PsycINFO (1967 to December 2009). We also searched reference lists and trials registers, handsearched journals and conference proceedings, and contacted experts.
Selection criteria: Randomised trials in adults after stroke where the intervention was specifically targeted at improving the eye movement disorder or improving the ability of the participant to cope with the eye movement disorder. The primary outcome was functional ability in activities of daily living. Secondary outcomes included functional ability in extended activities of daily living, eye movement measures, balance, falls, depression or anxiety, discharge destination or residence after stroke, quality of life and social isolation, adverse events, and death.
Data collection and analysis:
Two authors independently screened abstracts, extracted data and appraised trials. We undertook assessment of methodological quality for allocation concealment, blinding of outcome assessor, method of dealing with missing data, and other potential sources of bias.
Main results: Two studies (28 participants but only five were people with stroke) met the inclusion criteria and were included in this review. Both studies investigated pharmacological interventions for disorders of eye movement in patients with stroke. It was not appropriate to pool data and we were not able to draw conclusions from these studies. We found no other randomised studies which investigated interventions for disorders of eye movement in patients with stroke.
Authors' conclusions: There is insufficient evidence to reach conclusions about the effectiveness of interventions for patients with eye movement disorders after stroke. High quality research in the form of well-designed randomised trials are urgently required.
Original languageEnglish
Number of pages28
JournalCochrane Database of Systematic Reviews
Volume2011
Issue number10
DOIs
Publication statusPublished - Oct 2011

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Ocular Motility Disorders
Stroke
Aptitude
Activities of Daily Living
Bibliographic Databases
Depth Perception
Social Isolation
Eye Movements
MEDLINE
Patient Selection
Libraries
Reading
Rehabilitation
Anxiety
Hand

Keywords

  • eye movement disorders
  • stroke patients
  • interventions
  • medical trials

Cite this

Pollock, Alex ; Hazelton, Christine Roberta ; Henderson, Clair A. ; Angilley, Jayne ; Dhillon, Baljean ; Langhorne, Peter ; Livingstone, Katrina ; Munro, Frank A. ; Orr, Heather ; Rowe, Fiona J. ; Shahani, Uma. / Interventions for disorders of eye movement in patients with stroke. In: Cochrane Database of Systematic Reviews. 2011 ; Vol. 2011, No. 10.
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Pollock, A, Hazelton, CR, Henderson, CA, Angilley, J, Dhillon, B, Langhorne, P, Livingstone, K, Munro, FA, Orr, H, Rowe, FJ & Shahani, U 2011, 'Interventions for disorders of eye movement in patients with stroke', Cochrane Database of Systematic Reviews, vol. 2011, no. 10. https://doi.org/10.1002/14651858.CD008389.pub2

Interventions for disorders of eye movement in patients with stroke. / Pollock, Alex; Hazelton, Christine Roberta; Henderson, Clair A.; Angilley, Jayne; Dhillon, Baljean; Langhorne, Peter; Livingstone, Katrina ; Munro, Frank A.; Orr, Heather; Rowe, Fiona J.; Shahani, Uma.

In: Cochrane Database of Systematic Reviews, Vol. 2011, No. 10, 10.2011.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Interventions for disorders of eye movement in patients with stroke

AU - Pollock, Alex

AU - Hazelton, Christine Roberta

AU - Henderson, Clair A.

AU - Angilley, Jayne

AU - Dhillon, Baljean

AU - Langhorne, Peter

AU - Livingstone, Katrina

AU - Munro, Frank A.

AU - Orr, Heather

AU - Rowe, Fiona J.

AU - Shahani, Uma

PY - 2011/10

Y1 - 2011/10

N2 - Background: Eye movement disorders may affect over 70% of stroke patients. These eye movement disorders can result in difficulty maintaining the normal ocular position and difficulty moving the eyes appropriately. The resulting functional disabilities include a loss of depth perception, reduced hand-to-eye co-ordination, marked difficulties with near tasks and reading and reduced ability to scan the visual environment. They can also impact on the effectiveness of rehabilitation therapy. There are a wide variety of different treatment interventions proposed for eye movement disorders after stroke. However, in the past, there has been a lack of evidence specific to the impact of interventions on the functional outcome of patients with stroke.Objectives: To determine the effects of interventions for eye movement disorders on functional ability following stroke.Search methods: We searched the Cochrane Stroke Group Trials Register (February 2011), the Cochrane Eyes and Vision Group Trials Register (December 2009) and nine electronic bibliographic databases including CENTRAL (The Cochrane Library 2009, Issue 4), MEDLINE (1950 to December 2009), EMBASE (1980 to December 2009), CINAHL (1982 to December 2009), AMED (1985 to December 2009), and PsycINFO (1967 to December 2009). We also searched reference lists and trials registers, handsearched journals and conference proceedings, and contacted experts.Selection criteria: Randomised trials in adults after stroke where the intervention was specifically targeted at improving the eye movement disorder or improving the ability of the participant to cope with the eye movement disorder. The primary outcome was functional ability in activities of daily living. Secondary outcomes included functional ability in extended activities of daily living, eye movement measures, balance, falls, depression or anxiety, discharge destination or residence after stroke, quality of life and social isolation, adverse events, and death.Data collection and analysis: Two authors independently screened abstracts, extracted data and appraised trials. We undertook assessment of methodological quality for allocation concealment, blinding of outcome assessor, method of dealing with missing data, and other potential sources of bias.Main results: Two studies (28 participants but only five were people with stroke) met the inclusion criteria and were included in this review. Both studies investigated pharmacological interventions for disorders of eye movement in patients with stroke. It was not appropriate to pool data and we were not able to draw conclusions from these studies. We found no other randomised studies which investigated interventions for disorders of eye movement in patients with stroke.Authors' conclusions: There is insufficient evidence to reach conclusions about the effectiveness of interventions for patients with eye movement disorders after stroke. High quality research in the form of well-designed randomised trials are urgently required.

AB - Background: Eye movement disorders may affect over 70% of stroke patients. These eye movement disorders can result in difficulty maintaining the normal ocular position and difficulty moving the eyes appropriately. The resulting functional disabilities include a loss of depth perception, reduced hand-to-eye co-ordination, marked difficulties with near tasks and reading and reduced ability to scan the visual environment. They can also impact on the effectiveness of rehabilitation therapy. There are a wide variety of different treatment interventions proposed for eye movement disorders after stroke. However, in the past, there has been a lack of evidence specific to the impact of interventions on the functional outcome of patients with stroke.Objectives: To determine the effects of interventions for eye movement disorders on functional ability following stroke.Search methods: We searched the Cochrane Stroke Group Trials Register (February 2011), the Cochrane Eyes and Vision Group Trials Register (December 2009) and nine electronic bibliographic databases including CENTRAL (The Cochrane Library 2009, Issue 4), MEDLINE (1950 to December 2009), EMBASE (1980 to December 2009), CINAHL (1982 to December 2009), AMED (1985 to December 2009), and PsycINFO (1967 to December 2009). We also searched reference lists and trials registers, handsearched journals and conference proceedings, and contacted experts.Selection criteria: Randomised trials in adults after stroke where the intervention was specifically targeted at improving the eye movement disorder or improving the ability of the participant to cope with the eye movement disorder. The primary outcome was functional ability in activities of daily living. Secondary outcomes included functional ability in extended activities of daily living, eye movement measures, balance, falls, depression or anxiety, discharge destination or residence after stroke, quality of life and social isolation, adverse events, and death.Data collection and analysis: Two authors independently screened abstracts, extracted data and appraised trials. We undertook assessment of methodological quality for allocation concealment, blinding of outcome assessor, method of dealing with missing data, and other potential sources of bias.Main results: Two studies (28 participants but only five were people with stroke) met the inclusion criteria and were included in this review. Both studies investigated pharmacological interventions for disorders of eye movement in patients with stroke. It was not appropriate to pool data and we were not able to draw conclusions from these studies. We found no other randomised studies which investigated interventions for disorders of eye movement in patients with stroke.Authors' conclusions: There is insufficient evidence to reach conclusions about the effectiveness of interventions for patients with eye movement disorders after stroke. High quality research in the form of well-designed randomised trials are urgently required.

KW - eye movement disorders

KW - stroke patients

KW - interventions

KW - medical trials

U2 - 10.1002/14651858.CD008389.pub2

DO - 10.1002/14651858.CD008389.pub2

M3 - Article

VL - 2011

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

SN - 1469-493X

IS - 10

ER -