Innovative strategies for the elimination of viral hepatitis at a national level: a country case series

Sophia E. Schroeder, Alisa Pedrana, Nick Scott, David Wilson, Christian Kuschel, Lisa Aufegger, Rifat Atun, Ricardo Baptista-Leite, Maia Butsashvili, Manal El-Sayed, Aneley Getahun, Saeed Hamid, Radi Hammad, Ellen ‘t Hoen, Sharon J. Hutchinson, Jeffrey V. Lazarus, Olufunmilayo Lesi, Wangsheng Li, Rosmawati Binti Mohamed, Sigurdur OlafssonRaquel Peck, Annette H. Sohn, Mark Sonderup, Catherine W. Spearman, Tracy Swan, Mark Thursz, Tim Walker, Margaret Hellard, Jessica Howell

Research output: Contribution to journalArticle

Abstract

Viral hepatitis is a leading cause of morbidity and mortality worldwide, but has long been neglected by national and international policymakers. Recent modelling studies suggest that investing in the global elimination of viral hepatitis is feasible and cost-effective. In 2016, all 194 member states of the World Health Organization endorsed the goal to eliminate viral hepatitis as a public health threat by 2030, but complex systemic and social realities hamper implementation efforts. This paper presents eight case studies from a diverse range of countries that have invested in responses to viral hepatitis and adopted innovative approaches to tackle their respective epidemics. Based on an investment framework developed to build a global investment case for the elimination of viral hepatitis by 2030, national activities and key enablers are highlighted that showcase the feasibility and impact of concerted hepatitis responses across a range of settings, with different levels of available resources and infrastructural development. These case studies demonstrate the utility of taking a multipronged, public health approach to: (a) evidence-gathering and planning; (b) implementation; and (c) integration of viral hepatitis services into the Agenda for Sustainable Development. They provide models for planning, investment and implementation strategies for other countries facing similar challenges and resource constraints.

Original languageEnglish
Pages (from-to)1818-1836
Number of pages19
JournalLiver International
Volume39
Issue number10
Early online date21 Aug 2019
DOIs
Publication statusPublished - Oct 2019

Fingerprint

Hepatitis
Public Health
Virus Integration
Conservation of Natural Resources
Morbidity
Costs and Cost Analysis
Mortality

Keywords

  • viral hepatitis
  • morbidity
  • mortality
  • public health
  • developing countries
  • disease elimination
  • hepatitis B
  • hepatitis C
  • investment case
  • organizational case studies

Cite this

Schroeder, S. E., Pedrana, A., Scott, N., Wilson, D., Kuschel, C., Aufegger, L., ... Howell, J. (2019). Innovative strategies for the elimination of viral hepatitis at a national level: a country case series. Liver International, 39(10), 1818-1836. https://doi.org/10.1111/liv.14222
Schroeder, Sophia E. ; Pedrana, Alisa ; Scott, Nick ; Wilson, David ; Kuschel, Christian ; Aufegger, Lisa ; Atun, Rifat ; Baptista-Leite, Ricardo ; Butsashvili, Maia ; El-Sayed, Manal ; Getahun, Aneley ; Hamid, Saeed ; Hammad, Radi ; ‘t Hoen, Ellen ; Hutchinson, Sharon J. ; Lazarus, Jeffrey V. ; Lesi, Olufunmilayo ; Li, Wangsheng ; Mohamed, Rosmawati Binti ; Olafsson, Sigurdur ; Peck, Raquel ; Sohn, Annette H. ; Sonderup, Mark ; Spearman, Catherine W. ; Swan, Tracy ; Thursz, Mark ; Walker, Tim ; Hellard, Margaret ; Howell, Jessica. / Innovative strategies for the elimination of viral hepatitis at a national level: a country case series. In: Liver International. 2019 ; Vol. 39, No. 10. pp. 1818-1836.
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Schroeder, SE, Pedrana, A, Scott, N, Wilson, D, Kuschel, C, Aufegger, L, Atun, R, Baptista-Leite, R, Butsashvili, M, El-Sayed, M, Getahun, A, Hamid, S, Hammad, R, ‘t Hoen, E, Hutchinson, SJ, Lazarus, JV, Lesi, O, Li, W, Mohamed, RB, Olafsson, S, Peck, R, Sohn, AH, Sonderup, M, Spearman, CW, Swan, T, Thursz, M, Walker, T, Hellard, M & Howell, J 2019, 'Innovative strategies for the elimination of viral hepatitis at a national level: a country case series', Liver International, vol. 39, no. 10, pp. 1818-1836. https://doi.org/10.1111/liv.14222

Innovative strategies for the elimination of viral hepatitis at a national level: a country case series. / Schroeder, Sophia E. ; Pedrana, Alisa; Scott, Nick; Wilson, David ; Kuschel, Christian; Aufegger, Lisa ; Atun, Rifat; Baptista-Leite, Ricardo; Butsashvili, Maia; El-Sayed, Manal; Getahun, Aneley; Hamid, Saeed; Hammad, Radi; ‘t Hoen, Ellen; Hutchinson, Sharon J.; Lazarus, Jeffrey V.; Lesi, Olufunmilayo; Li, Wangsheng ; Mohamed, Rosmawati Binti; Olafsson, Sigurdur; Peck, Raquel; Sohn, Annette H. ; Sonderup, Mark; Spearman, Catherine W.; Swan, Tracy; Thursz, Mark; Walker, Tim; Hellard, Margaret; Howell, Jessica.

In: Liver International, Vol. 39, No. 10, 10.2019, p. 1818-1836.

Research output: Contribution to journalArticle

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AU - Schroeder, Sophia E.

AU - Pedrana, Alisa

AU - Scott, Nick

AU - Wilson, David

AU - Kuschel, Christian

AU - Aufegger, Lisa

AU - Atun, Rifat

AU - Baptista-Leite, Ricardo

AU - Butsashvili, Maia

AU - El-Sayed, Manal

AU - Getahun, Aneley

AU - Hamid, Saeed

AU - Hammad, Radi

AU - ‘t Hoen, Ellen

AU - Hutchinson, Sharon J.

AU - Lazarus, Jeffrey V.

AU - Lesi, Olufunmilayo

AU - Li, Wangsheng

AU - Mohamed, Rosmawati Binti

AU - Olafsson, Sigurdur

AU - Peck, Raquel

AU - Sohn, Annette H.

AU - Sonderup, Mark

AU - Spearman, Catherine W.

AU - Swan, Tracy

AU - Thursz, Mark

AU - Walker, Tim

AU - Hellard, Margaret

AU - Howell, Jessica

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KW - morbidity

KW - mortality

KW - public health

KW - developing countries

KW - disease elimination

KW - hepatitis B

KW - hepatitis C

KW - investment case

KW - organizational case studies

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Schroeder SE, Pedrana A, Scott N, Wilson D, Kuschel C, Aufegger L et al. Innovative strategies for the elimination of viral hepatitis at a national level: a country case series. Liver International. 2019 Oct;39(10):1818-1836. https://doi.org/10.1111/liv.14222