Infections with spore-forming bacteria in persons who inject drugs, 2000-2009

Norah E. Palmateer, Vivian D. Hope, Kirsty Roy, Andrea Marongiu, Joanne M. White, Kathie A. Grant, Colin N. Ramsay, David Goldberg, Fortune Ncube

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Abstract

Since 2000 in the United Kingdom, infections caused by spore-forming bacteria have been associated with increasing illness and death among persons who inject drugs (PWID). To assess temporal and geographic trends in these illnesses (botulism, tetanus, Clostridium novyi infection, and anthrax), we compared rates across England and Scotland for 2000–2009. Overall, 295 infections were reported: 1.45 per 1,000 PWID in England and 4.01 per 1,000 PWID in Scotland. The higher rate in Scotland was mainly attributable to C. novyi infection and anthrax; rates of botulism and tetanus were comparable in both countries. The temporal and geographic clustering of cases of C. novyi and anthrax into outbreaks suggests possible contamination of specific heroin batches; in contrast, the more sporadic nature of tetanus and botulism cases suggests that these spores might more commonly exist in the drug supply or local environment although at varying levels. PWID should be advised about treatment programs, injecting hygiene, risks, and vaccinations.
Original languageEnglish
Pages (from-to)29-34
Number of pages6
JournalEmerging Infectious Diseases
Volume19
Issue number1
DOIs
Publication statusPublished - Jan 2013

Fingerprint

Spores
Botulism
Anthrax
Bacteria
Tetanus
Scotland
Infection
Pharmaceutical Preparations
England
Clostridium Infections
Heroin
Hygiene
Disease Outbreaks
Cluster Analysis
Vaccination
Therapeutics

Keywords

  • PWID
  • spore-forming bacteria
  • infectious diseases
  • data analysis
  • demographic characteristics

Cite this

Palmateer, N. E., Hope, V. D., Roy, K., Marongiu, A., White, J. M., Grant, K. A., ... Ncube, F. (2013). Infections with spore-forming bacteria in persons who inject drugs, 2000-2009. Emerging Infectious Diseases, 19(1), 29-34. https://doi.org/10.3201/eid1901.120044
Palmateer, Norah E. ; Hope, Vivian D. ; Roy, Kirsty ; Marongiu, Andrea ; White, Joanne M. ; Grant, Kathie A. ; Ramsay, Colin N. ; Goldberg, David ; Ncube, Fortune. / Infections with spore-forming bacteria in persons who inject drugs, 2000-2009. In: Emerging Infectious Diseases. 2013 ; Vol. 19, No. 1. pp. 29-34.
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Palmateer, NE, Hope, VD, Roy, K, Marongiu, A, White, JM, Grant, KA, Ramsay, CN, Goldberg, D & Ncube, F 2013, 'Infections with spore-forming bacteria in persons who inject drugs, 2000-2009', Emerging Infectious Diseases, vol. 19, no. 1, pp. 29-34. https://doi.org/10.3201/eid1901.120044

Infections with spore-forming bacteria in persons who inject drugs, 2000-2009. / Palmateer, Norah E.; Hope, Vivian D.; Roy, Kirsty; Marongiu, Andrea; White, Joanne M.; Grant, Kathie A.; Ramsay, Colin N.; Goldberg, David; Ncube, Fortune.

In: Emerging Infectious Diseases, Vol. 19, No. 1, 01.2013, p. 29-34.

Research output: Contribution to journalArticle

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