Increased urinary excretion of glycosaminoglycans in insulin-dependent diabetic patients with limited joint mobility

G. C. Priestley*, A. Collier, D. M. Matthews, B. F. Clarke

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Urinary excretion of glycosaminoglycans (GAG) was measured in 24-h specimens collected from 27 insulin-dependent male diabetic patients and 22 healthy males of similar ages. Excretion relative to creatinine was increased by 35% in the diabetic group as a whole (p< 0.02). Twelve patients with limited joint mobility (cheiroarthropathy) formed a subgroup with high excretion (69% above controls), those without limited joint mobility being similar to controls. There was no correlation of retinopathy with GAG excretion.
Original languageEnglish
Pages (from-to)462-464
Number of pages3
JournalRheumatology
Volume27
Issue number6
DOIs
Publication statusPublished - Dec 1988
Externally publishedYes

Keywords

  • Cheiroarthropathy.
  • Glycosaminoglycans
  • Insulin-dependent diabetes

ASJC Scopus subject areas

  • Rheumatology
  • Pharmacology (medical)

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