In-vivo confocal microscopy of the corneal endothelium: comparison of three morphometry methods after corneal transplantation

Sven Jonuscheit, Michael Doughty, Kanna Ramaesh

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to assess the endothelium of corneal grafts by in vivo confocal microscopy (IVCM), and to evaluate an automated endothelial software system in comparison with a manual cell count and planimetry. Overall, 40 corneal grafts (20 deep anterior lamellar keratoplasties (DALKs) and 20 penetrating keratoplasties (PKs)) were assessed by scanning-slit IVCM. The endothelial cell density (ECD) was estimated with the automated and the manual cell count method of the instrument's Nidek Advanced Vision Information System (NAVIS) software. The results were compared with planimetry as the reference method, and the agreement was assessed.

Original languageEnglish
Pages (from-to)1130-1137
Number of pages8
JournalEye
Volume25
Issue number9
DOIs
Publication statusPublished - 1 Sep 2011

Keywords

  • corneal transplants
  • corneal endothelium
  • vision sciences
  • confocal microscopy

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