Impact of age and menopausal status on the postprandial triacylglycerol response in healthy women

Kim G. Jackson; Elizheeba Abraham; Adrian M. Smith; Peter Murray; Brendan O’Malley; Christine M. Williams; Anne M. Minihane

doi:10.1016/j.atherosclerosis.2009.06.030

Impact of age and menopausal status on the postprandial triacylglycerol response in healthy women

Kim G. Jackson, Elizheeba Abraham, Adrian M. Smith, Peter Murray, Brendan O’Malley, Christine M. Williams, Anne M. Minihane

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Thirty-seven premenopausal and sixty-one postmenopausal women underwent a sequential meal postprandial investigation, in which blood samples were taken at regular intervals after a test breakfast and lunch given at 0 and 330 min respectively. Lipids and glucose were measured in the fasting sample, with TAG analysed in the postprandial samples. Postmenopausal women were shown to have higher fasting total cholesterol, low density lipoprotein cholesterol (LDL-C) and glucose (P <0.02). Marked differences in the postprandial TAG response were evident between the groups, with a greater incremental area under the curve (IAUC) and maximum TAG concentration in the postmenopausal women (P <0.04). Multivariate regression analysis revealed both age and fasting TAG to be independently associated with the summary measures of the postprandial TAG response in the premenopausal women only.

Original language	English
Pages (from-to)	246-252
Number of pages	7
Journal	Atherosclerosis
Volume	208
Issue number	1
DOIs	https://doi.org/10.1016/j.atherosclerosis.2009.06.030
Publication status	Published - 1 Jan 2010

Keywords

postprandial triacylglycerol response
age
menopause
women

Documents and Links

10.1016/j.atherosclerosis.2009.06.030

Cite this

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title = "Impact of age and menopausal status on the postprandial triacylglycerol response in healthy women",

abstract = "Thirty-seven premenopausal and sixty-one postmenopausal women underwent a sequential meal postprandial investigation, in which blood samples were taken at regular intervals after a test breakfast and lunch given at 0 and 330 min respectively. Lipids and glucose were measured in the fasting sample, with TAG analysed in the postprandial samples. Postmenopausal women were shown to have higher fasting total cholesterol, low density lipoprotein cholesterol (LDL-C) and glucose (P <0.02). Marked differences in the postprandial TAG response were evident between the groups, with a greater incremental area under the curve (IAUC) and maximum TAG concentration in the postmenopausal women (P <0.04). Multivariate regression analysis revealed both age and fasting TAG to be independently associated with the summary measures of the postprandial TAG response in the premenopausal women only.",

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T1 - Impact of age and menopausal status on the postprandial triacylglycerol response in healthy women

AU - Jackson, Kim G.

AU - Abraham, Elizheeba

AU - Smith, Adrian M.

AU - Murray, Peter

AU - O’Malley, Brendan

AU - Williams, Christine M.

AU - Minihane, Anne M.

N1 - <p>Originally published in: Atherosclerosis (2010), 208 (1), pp.246-252.</p>

PY - 2010/1/1

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N2 - Thirty-seven premenopausal and sixty-one postmenopausal women underwent a sequential meal postprandial investigation, in which blood samples were taken at regular intervals after a test breakfast and lunch given at 0 and 330 min respectively. Lipids and glucose were measured in the fasting sample, with TAG analysed in the postprandial samples. Postmenopausal women were shown to have higher fasting total cholesterol, low density lipoprotein cholesterol (LDL-C) and glucose (P <0.02). Marked differences in the postprandial TAG response were evident between the groups, with a greater incremental area under the curve (IAUC) and maximum TAG concentration in the postmenopausal women (P <0.04). Multivariate regression analysis revealed both age and fasting TAG to be independently associated with the summary measures of the postprandial TAG response in the premenopausal women only.

AB - Thirty-seven premenopausal and sixty-one postmenopausal women underwent a sequential meal postprandial investigation, in which blood samples were taken at regular intervals after a test breakfast and lunch given at 0 and 330 min respectively. Lipids and glucose were measured in the fasting sample, with TAG analysed in the postprandial samples. Postmenopausal women were shown to have higher fasting total cholesterol, low density lipoprotein cholesterol (LDL-C) and glucose (P <0.02). Marked differences in the postprandial TAG response were evident between the groups, with a greater incremental area under the curve (IAUC) and maximum TAG concentration in the postmenopausal women (P <0.04). Multivariate regression analysis revealed both age and fasting TAG to be independently associated with the summary measures of the postprandial TAG response in the premenopausal women only.

KW - postprandial triacylglycerol response

KW - age

KW - menopause

KW - women

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JF - Atherosclerosis

IS - 1

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Impact of age and menopausal status on the postprandial triacylglycerol response in healthy women

Abstract

Keywords

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