Healthcare-associated pneumonia in acute care hospitals in European Union/European Economic Area countries: an analysis of data from a point prevalence survey, 2011 to 2012

Jan Walter, Sebastian Haller, Chantal Quinten, Tommi Kärki, Benedikt Zacher, Tim Eckmanns, Muna Abu Sin, Diamantis Plachouras, Pete Kinross, Carl Suetens, ECDC PPS Study Group

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Abstract

An aim of the ECDC point prevalence survey (PPS) in European Union/European Economic Area acute care hospitals was to acquire standardised healthcare-associated infections (HAI) data. We analysed one of the most common HAIs in the ECDC PPS, healthcare-associated pneumonia (HAP). Standardised HAI case definitions were provided and countries were advised to recruit nationally representative subsets of hospitals. We calculated 95% confidence intervals (CIs) around prevalence estimates and adjusted for clustering at hospital level. Of 231,459 patients in the survey, 2,902 (1.3%; 95% CI: 1.2–1.3) fulfilled the case definition for a HAP. HAPs were most frequent in intensive care units (8.1%; 95% CI: 7.4–8.9) and among patients intubated on the day of the survey (15%; 95% CI: 14–17; n = 737 with HAP). The most frequently reported microorganism was Pseudomonas aeruginosa (17% of 1,403 isolates), followed by Staphylococcus aureus (12%) and Klebsiella spp. (12%). Antimicrobial resistance was common among isolated microorganisms. The most frequently prescribed antimicrobial group was penicillins, including combinations with beta-lactamase inhibitors. HAPs occur regularly among intubated and non-intubated patients, with marked differences between medical specialities. HAPs remain a priority for preventive interventions, including surveillance. Our data provide a reference for future prevalence of HAPs at various settings.
Original languageEnglish
JournalEurosurveillance
Volume23
Issue number32
DOIs
Publication statusPublished - 9 Aug 2018

Keywords

  • healthcare-associated infection
  • pneumonia
  • epidemiology
  • surveillance
  • antimicrobial resistance
  • antibiotic use
  • infection prevention and control
  • point prevalence survey
  • Europe

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    Walter, J., Haller, S., Quinten, C., Kärki, T., Zacher, B., Eckmanns, T., Sin, M. A., Plachouras, D., Kinross, P., Suetens, C., & ECDC PPS Study Group (2018). Healthcare-associated pneumonia in acute care hospitals in European Union/European Economic Area countries: an analysis of data from a point prevalence survey, 2011 to 2012. Eurosurveillance, 23(32). https://doi.org/10.2807/1560-7917.ES.2018.23.32.1700843