Glucomannan hydrolysate (GMH) inhibition of Candida albicans growth in the presence of Lactobacillus and Lactococcus species

Alistair D. Sutherland; Richard F. Tester; Farage H. Al-Ghazzewi; Elaine McCulloch; Michael Connolly

doi:10.1080/08910600802355726

Glucomannan hydrolysate (GMH) inhibition of Candida albicans growth in the presence of Lactobacillus and Lactococcus species

Alistair D. Sutherland, Richard F. Tester, Farage H. Al-Ghazzewi, Elaine McCulloch, Michael Connolly

Biological and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Konjac glucomannan hydrolysate (GMH) was compared with inulin and glucose for its capacity to support the growth of probiotic bacteria but inhibit the growth of Candida albicans in vitro. The growth of lactic acid bacteria (LAB) was studied under aerobic, anaerobic and 5% CO₂ conditions where the GMH progressively supported the growth of LAB as a function of concentration (0.1, 0.5, 1.0 and 2.0% w/v). In mixed cultures, GMH promoted the growth of LAB (even at concentrations as low as 0.1%) and consequently increased inhibition of C. albicans under anaerobic conditions, 5% CO₂ or aerobic conditions. Inhibition of C. albicans growth was generally higher than that with glucose or inulin and, of the LAB strains, Lactobacillus jensenii exhibited most inhibition of the pathogen.
/08910600802355726

Original language	English
Pages (from-to)	127-134
Number of pages	8
Journal	Microbial Ecology in Health and Disease
Volume	20
Issue number	3
DOIs	https://doi.org/10.1080/08910600802355726
Publication status	Published - 1 Jan 2008

Keywords

probiotics
Candida albicans
prebiotic

Documents and Links

10.1080/08910600802355726

Cite this

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title = "Glucomannan hydrolysate (GMH) inhibition of Candida albicans growth in the presence of Lactobacillus and Lactococcus species",

abstract = "Konjac glucomannan hydrolysate (GMH) was compared with inulin and glucose for its capacity to support the growth of probiotic bacteria but inhibit the growth of Candida albicans in vitro. The growth of lactic acid bacteria (LAB) was studied under aerobic, anaerobic and 5% CO2 conditions where the GMH progressively supported the growth of LAB as a function of concentration (0.1, 0.5, 1.0 and 2.0% w/v). In mixed cultures, GMH promoted the growth of LAB (even at concentrations as low as 0.1%) and consequently increased inhibition of C. albicans under anaerobic conditions, 5% CO2 or aerobic conditions. Inhibition of C. albicans growth was generally higher than that with glucose or inulin and, of the LAB strains, Lactobacillus jensenii exhibited most inhibition of the pathogen. /08910600802355726",

keywords = "probiotics, Candida albicans, prebiotic",

author = "Sutherland, {Alistair D.} and Tester, {Richard F.} and Al-Ghazzewi, {Farage H.} and Elaine McCulloch and Michael Connolly",

note = "<p>Originally published in: Microbial Ecology in Health and Disease (2008), 20 (3), pp.127-134.</p>",

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Glucomannan hydrolysate (GMH) inhibition of Candida albicans growth in the presence of Lactobacillus and Lactococcus species. / Sutherland, Alistair D.; Tester, Richard F.; Al-Ghazzewi, Farage H.; McCulloch, Elaine; Connolly, Michael.

In: Microbial Ecology in Health and Disease, Vol. 20, No. 3, 01.01.2008, p. 127-134.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Glucomannan hydrolysate (GMH) inhibition of Candida albicans growth in the presence of Lactobacillus and Lactococcus species

AU - Sutherland, Alistair D.

AU - Tester, Richard F.

AU - Al-Ghazzewi, Farage H.

AU - McCulloch, Elaine

AU - Connolly, Michael

N1 - <p>Originally published in: Microbial Ecology in Health and Disease (2008), 20 (3), pp.127-134.</p>

PY - 2008/1/1

Y1 - 2008/1/1

N2 - Konjac glucomannan hydrolysate (GMH) was compared with inulin and glucose for its capacity to support the growth of probiotic bacteria but inhibit the growth of Candida albicans in vitro. The growth of lactic acid bacteria (LAB) was studied under aerobic, anaerobic and 5% CO2 conditions where the GMH progressively supported the growth of LAB as a function of concentration (0.1, 0.5, 1.0 and 2.0% w/v). In mixed cultures, GMH promoted the growth of LAB (even at concentrations as low as 0.1%) and consequently increased inhibition of C. albicans under anaerobic conditions, 5% CO2 or aerobic conditions. Inhibition of C. albicans growth was generally higher than that with glucose or inulin and, of the LAB strains, Lactobacillus jensenii exhibited most inhibition of the pathogen. /08910600802355726

AB - Konjac glucomannan hydrolysate (GMH) was compared with inulin and glucose for its capacity to support the growth of probiotic bacteria but inhibit the growth of Candida albicans in vitro. The growth of lactic acid bacteria (LAB) was studied under aerobic, anaerobic and 5% CO2 conditions where the GMH progressively supported the growth of LAB as a function of concentration (0.1, 0.5, 1.0 and 2.0% w/v). In mixed cultures, GMH promoted the growth of LAB (even at concentrations as low as 0.1%) and consequently increased inhibition of C. albicans under anaerobic conditions, 5% CO2 or aerobic conditions. Inhibition of C. albicans growth was generally higher than that with glucose or inulin and, of the LAB strains, Lactobacillus jensenii exhibited most inhibition of the pathogen. /08910600802355726

KW - probiotics

KW - Candida albicans

KW - prebiotic

U2 - 10.1080/08910600802355726

DO - 10.1080/08910600802355726

M3 - Article

VL - 20

SP - 127

EP - 134

JO - Microbial Ecology in Health and Disease

JF - Microbial Ecology in Health and Disease

SN - 0891-060X

IS - 3

ER -

Glucomannan hydrolysate (GMH) inhibition of Candida albicans growth in the presence of Lactobacillus and Lactococcus species

Abstract

Keywords

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