Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions

Laura Cavicchioli; Rossella Zanetti; Serena Ferraresso; Claire Crossan; Peter A. Barry; Massimo Boldrin; Marta Vadori; Silvia Ferro; Fiorella Calabrese; Linda Scobie; Emanuele Cozzi; Valentina Zappulli

doi:10.1111/xen.12153

Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions

Laura Cavicchioli, Rossella Zanetti, Serena Ferraresso, Claire Crossan, Peter A. Barry, Massimo Boldrin, Marta Vadori, Silvia Ferro, Fiorella Calabrese, Linda Scobie, Emanuele Cozzi, Valentina Zappulli

Biological and Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Xenotransplantation is a potential answer to the current organ shortage, but the risk of infections related to overimmunosuppression is an important parameter that may predict the recipient's long-term survival. Cytomegalovirus (CMV) in xenotransplanted and immunosuppressed primates is a well-known cause of disease particularly affecting the gastrointestinal (GI) tract and a zoonotic concern

Original language	English
Pages (from-to)	135–143
Number of pages	9
Journal	Xenotransplantation
Volume	22
Issue number	2
Early online date	12 Feb 2015
DOIs	https://doi.org/10.1111/xen.12153
Publication status	Published - Mar 2015

Keywords

cytomegalovirus
infections
immunosuppression

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10.1111/xen.12153

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Cavicchioli, L., Zanetti, R., Ferraresso, S., Crossan, C., Barry, P. A., Boldrin, M., Vadori, M., Ferro, S., Calabrese, F., Scobie, L., Cozzi, E., & Zappulli, V. (2015). Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions. Xenotransplantation, 22(2), 135–143. https://doi.org/10.1111/xen.12153

Cavicchioli, Laura ; Zanetti, Rossella ; Ferraresso, Serena ; Crossan, Claire ; Barry, Peter A. ; Boldrin, Massimo ; Vadori, Marta ; Ferro, Silvia ; Calabrese, Fiorella ; Scobie, Linda ; Cozzi, Emanuele ; Zappulli, Valentina. / Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions. In: Xenotransplantation. 2015 ; Vol. 22, No. 2. pp. 135–143.

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abstract = "Xenotransplantation is a potential answer to the current organ shortage, but the risk of infections related to overimmunosuppression is an important parameter that may predict the recipient's long-term survival. Cytomegalovirus (CMV) in xenotransplanted and immunosuppressed primates is a well-known cause of disease particularly affecting the gastrointestinal (GI) tract and a zoonotic concern",

keywords = "cytomegalovirus, infections , immunosuppression",

author = "Laura Cavicchioli and Rossella Zanetti and Serena Ferraresso and Claire Crossan and Barry, {Peter A.} and Massimo Boldrin and Marta Vadori and Silvia Ferro and Fiorella Calabrese and Linda Scobie and Emanuele Cozzi and Valentina Zappulli",

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Cavicchioli, L, Zanetti, R, Ferraresso, S, Crossan, C, Barry, PA, Boldrin, M, Vadori, M, Ferro, S, Calabrese, F, Scobie, L, Cozzi, E & Zappulli, V 2015, 'Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions', Xenotransplantation, vol. 22, no. 2, pp. 135–143. https://doi.org/10.1111/xen.12153

Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions. / Cavicchioli, Laura; Zanetti, Rossella; Ferraresso, Serena; Crossan, Claire; Barry, Peter A.; Boldrin, Massimo; Vadori, Marta; Ferro, Silvia; Calabrese, Fiorella; Scobie, Linda; Cozzi, Emanuele; Zappulli, Valentina.

In: Xenotransplantation, Vol. 22, No. 2, 03.2015, p. 135–143.

Research output: Contribution to journal › Article › peer-review

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T1 - Expression of recipient cytomegalovirus in immunosuppressed and xenotransplanted Macaca fascicularis may be related to more severe gastrointestinal lesions

AU - Cavicchioli, Laura

AU - Zanetti, Rossella

AU - Ferraresso, Serena

AU - Crossan, Claire

AU - Barry, Peter A.

AU - Boldrin, Massimo

AU - Vadori, Marta

AU - Ferro, Silvia

AU - Calabrese, Fiorella

AU - Scobie, Linda

AU - Cozzi, Emanuele

AU - Zappulli, Valentina

PY - 2015/3

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AB - Xenotransplantation is a potential answer to the current organ shortage, but the risk of infections related to overimmunosuppression is an important parameter that may predict the recipient's long-term survival. Cytomegalovirus (CMV) in xenotransplanted and immunosuppressed primates is a well-known cause of disease particularly affecting the gastrointestinal (GI) tract and a zoonotic concern

KW - cytomegalovirus

KW - infections

KW - immunosuppression

U2 - 10.1111/xen.12153

DO - 10.1111/xen.12153

M3 - Article

VL - 22

SP - 135

EP - 143

JO - Xenotransplantation

JF - Xenotransplantation

SN - 0908-665X

IS - 2

ER -