Excess liver-related morbidity of chronic hepatitis C patients, who achieve a sustained viral response, and are discharged from care

Hamish Innes, Sharon Hutchinson, Samuel Allen, Diptendu Bhattacharyya (Editor), Peter Bramley, Toby E. S. Delahooke, John F Dillon, Ewan Forrest, Andrew Fraser, Ruth Gillespie, David Goldberg, Nicholas Kennedy, Scott McDonald, Allan McLeod, Peter R Mills, Judith Morris, Peter Hayes

Research output: Contribution to journalArticlepeer-review

Abstract

Our objective was to address two shortfalls in the hepatitis C virus (HCV) literature: (1) Few data exist comparing post-treatment liver-related mortality/morbidity in HCV-sustained virologic response (SVR) patients to non-SVR patients and (2) no data exist examining liver-related morbidity among treatment response subgroups, particularly among noncirrhotic SVR patients, a group who in the main are discharged from care without further follow-up. A retrospective cohort of 1,215 previously naïve HCV interferon patients (treated 1996-2007) was derived using HCV clinical databases from nine Scottish clinics.
Original languageEnglish
Pages (from-to)1547-58
Number of pages12
JournalHepatology
Volume54
Issue number5
DOIs
Publication statusPublished - Nov 2011

Keywords

  • hepatitis C
  • clinical databases
  • liver cirrhosis

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