Excess liver-related morbidity of chronic hepatitis C patients, who achieve a sustained viral response, and are discharged from care

Hamish  Innes; Sharon Hutchinson; Samuel Allen; Diptendu Bhattacharyya; Peter Bramley; Toby E. S.  Delahooke; John F  Dillon; Ewan  Forrest; Andrew Fraser; Ruth Gillespie; David Goldberg; Nicholas Kennedy; Scott  McDonald; Allan McLeod; Peter R Mills; Judith  Morris; Peter  Hayes

doi:10.1002/hep.24561

Excess liver-related morbidity of chronic hepatitis C patients, who achieve a sustained viral response, and are discharged from care

Hamish Innes, Sharon Hutchinson, Samuel Allen, Diptendu Bhattacharyya (Editor), Peter Bramley, Toby E. S. Delahooke, John F Dillon, Ewan Forrest, Andrew Fraser, Ruth Gillespie, David Goldberg, Nicholas Kennedy, Scott McDonald, Allan McLeod, Peter R Mills, Judith Morris, Peter Hayes

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Abstract

Our objective was to address two shortfalls in the hepatitis C virus (HCV) literature: (1) Few data exist comparing post-treatment liver-related mortality/morbidity in HCV-sustained virologic response (SVR) patients to non-SVR patients and (2) no data exist examining liver-related morbidity among treatment response subgroups, particularly among noncirrhotic SVR patients, a group who in the main are discharged from care without further follow-up. A retrospective cohort of 1,215 previously naïve HCV interferon patients (treated 1996-2007) was derived using HCV clinical databases from nine Scottish clinics.

Original language	English
Pages (from-to)	1547-58
Number of pages	12
Journal	Hepatology
Volume	54
Issue number	5
DOIs	https://doi.org/10.1002/hep.24561
Publication status	Published - Nov 2011

Keywords

hepatitis C
clinical databases
liver cirrhosis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/hep.24561

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Innes, H., Hutchinson, S., Allen, S., Bhattacharyya, D. (Ed.), Bramley, P., Delahooke, T. E. S., Dillon, J. F., Forrest, E., Fraser, A., Gillespie, R., Goldberg, D., Kennedy, N., McDonald, S., McLeod, A., Mills, P. R., Morris, J., & Hayes, P. (2011). Excess liver-related morbidity of chronic hepatitis C patients, who achieve a sustained viral response, and are discharged from care. Hepatology, 54(5), 1547-58. https://doi.org/10.1002/hep.24561

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abstract = "Our objective was to address two shortfalls in the hepatitis C virus (HCV) literature: (1) Few data exist comparing post-treatment liver-related mortality/morbidity in HCV-sustained virologic response (SVR) patients to non-SVR patients and (2) no data exist examining liver-related morbidity among treatment response subgroups, particularly among noncirrhotic SVR patients, a group who in the main are discharged from care without further follow-up. A retrospective cohort of 1,215 previously na{\"i}ve HCV interferon patients (treated 1996-2007) was derived using HCV clinical databases from nine Scottish clinics.",

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Innes, H, Hutchinson, S, Allen, S, Bhattacharyya, D (ed.), Bramley, P, Delahooke, TES, Dillon, JF, Forrest, E, Fraser, A, Gillespie, R, Goldberg, D, Kennedy, N, McDonald, S, McLeod, A, Mills, PR, Morris, J & Hayes, P 2011, 'Excess liver-related morbidity of chronic hepatitis C patients, who achieve a sustained viral response, and are discharged from care', Hepatology, vol. 54, no. 5, pp. 1547-58. https://doi.org/10.1002/hep.24561

TY - JOUR

T1 - Excess liver-related morbidity of chronic hepatitis C patients, who achieve a sustained viral response, and are discharged from care

AU - Innes, Hamish

AU - Hutchinson, Sharon

AU - Allen, Samuel

AU - Bramley, Peter

AU - Delahooke, Toby E. S.

AU - Dillon, John F

AU - Forrest, Ewan

AU - Fraser, Andrew

AU - Gillespie, Ruth

AU - Goldberg, David

AU - Kennedy, Nicholas

AU - McDonald, Scott

AU - McLeod, Allan

AU - Mills, Peter R

AU - Morris, Judith

AU - Hayes, Peter

A2 - Bhattacharyya, Diptendu

PY - 2011/11

Y1 - 2011/11

N2 - Our objective was to address two shortfalls in the hepatitis C virus (HCV) literature: (1) Few data exist comparing post-treatment liver-related mortality/morbidity in HCV-sustained virologic response (SVR) patients to non-SVR patients and (2) no data exist examining liver-related morbidity among treatment response subgroups, particularly among noncirrhotic SVR patients, a group who in the main are discharged from care without further follow-up. A retrospective cohort of 1,215 previously naïve HCV interferon patients (treated 1996-2007) was derived using HCV clinical databases from nine Scottish clinics.

AB - Our objective was to address two shortfalls in the hepatitis C virus (HCV) literature: (1) Few data exist comparing post-treatment liver-related mortality/morbidity in HCV-sustained virologic response (SVR) patients to non-SVR patients and (2) no data exist examining liver-related morbidity among treatment response subgroups, particularly among noncirrhotic SVR patients, a group who in the main are discharged from care without further follow-up. A retrospective cohort of 1,215 previously naïve HCV interferon patients (treated 1996-2007) was derived using HCV clinical databases from nine Scottish clinics.

KW - hepatitis C

KW - clinical databases

KW - liver cirrhosis

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AN - SCOPUS:80055035674

VL - 54

SP - 1547

EP - 1558

JO - Hepatology

JF - Hepatology

IS - 5

ER -

Excess liver-related morbidity of chronic hepatitis C patients, who achieve a sustained viral response, and are discharged from care

Abstract

Keywords

UN SDGs

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