Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 408-412 |
| Number of pages | 5 |
| Journal | Contraception |
| Volume | 88 |
| Issue number | 3 |
| Early online date | 7 Dec 2012 |
| DOIs | |
| Publication status | Published - Sep 2013 |
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Keywords
- estrogen
- progesterone
- athletic performance
- experimental group
- control group
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Examining the role of oral contraceptive users as an experimental and/or control group in athletic performance studies. / Elliot-Sale, Kirsty Jayne; Smith, Stephanie; Bacon, James ; Clayton, David; McPhilimey, Martin; Goutianos, Georgios; Hampson, Jennifer; Sale, Craig.
In: Contraception, Vol. 88, No. 3, 09.2013, p. 408-412.Research output: Contribution to journal › Article
TY - JOUR
T1 - Examining the role of oral contraceptive users as an experimental and/or control group in athletic performance studies
AU - Elliot-Sale, Kirsty Jayne
AU - Smith, Stephanie
AU - Bacon, James
AU - Clayton, David
AU - McPhilimey, Martin
AU - Goutianos, Georgios
AU - Hampson, Jennifer
AU - Sale, Craig
PY - 2013/9
Y1 - 2013/9
N2 - Background: This study was conducted to examine the effect of oral contraceptives on endogenous reproductive hormone levels in order to assess the suitability of oral contraceptive users as experimental and/or control groups in human performance studies. Study Design: Ninety-five females who were taking a variety of oral contraceptives (2 types and 11 brands) were recruited. A single blood sample was analysed for endogenous concentrations of oestradiol and progesterone. Results: There were significant differences (p<.05) in circulating oestradiol and progesterone as a result of oral contraceptive type and brand. Overall, oral contraceptive use resulted in low levels of oestradiol and progesterone and large variation in hormone concentration when multiple brands were analysed together. Conclusion: This study indicates that future studies should employ a single pill type and brand when using oral contraceptive users as either a control or experimental group and that comparison between oral contraceptive users as a control group and the early follicular phase of the menstrual cycle as an experimental group should be reconsidered.
AB - Background: This study was conducted to examine the effect of oral contraceptives on endogenous reproductive hormone levels in order to assess the suitability of oral contraceptive users as experimental and/or control groups in human performance studies. Study Design: Ninety-five females who were taking a variety of oral contraceptives (2 types and 11 brands) were recruited. A single blood sample was analysed for endogenous concentrations of oestradiol and progesterone. Results: There were significant differences (p<.05) in circulating oestradiol and progesterone as a result of oral contraceptive type and brand. Overall, oral contraceptive use resulted in low levels of oestradiol and progesterone and large variation in hormone concentration when multiple brands were analysed together. Conclusion: This study indicates that future studies should employ a single pill type and brand when using oral contraceptive users as either a control or experimental group and that comparison between oral contraceptive users as a control group and the early follicular phase of the menstrual cycle as an experimental group should be reconsidered.
KW - estrogen
KW - progesterone
KW - athletic performance
KW - experimental group
KW - control group
U2 - 10.1016/j.contraception.2012.11.023
DO - 10.1016/j.contraception.2012.11.023
M3 - Article
VL - 88
SP - 408
EP - 412
JO - Contraception
JF - Contraception
SN - 0010-7824
IS - 3
ER -