Evidence of purinergic neurotransmission in isolated, intact horse sweat glands

Douglas Bovell, Christopher M. Riggs, Gordon Sidlow, Suzanne Troester, William MacLaren, Wallace Yip, Wing H. Ko

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Fluid secretion by sweat glands in response to heat and exercise is underpinned by increases in intracellular calcium. In horses, this is primarily via ß2-adrenoceptors, but studies in equine sweat gland cell lines have indicated a possible role for purinergic agonists. Knowledge of equine sweating stimulus–secretion mechanisms in intact glands from healthy animals would allow future comparison to determine whether these mechanisms are affected in equine anhidrosis.
Original languageEnglish
Pages (from-to)398-403
Number of pages6
JournalVeterinary Dermatology
Issue number4
Early online date10 Jun 2013
Publication statusPublished - Aug 2013


  • equine sweat glands
  • fluid secretion
  • intracellular calcium
  • equine anhidrosis


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