Evidence for a relative thinning of the preipheral cornea with age in white European subjects

The purpose of this study was to investigate age-related differences in central and peripheral corneal thickness in humans with univariate and multivariate regression analyses. Orbscan II (Bausch & Lomb, Inc., Rochester, NY) pachymetry was used to assess the cornea in healthy, white European subjects. A corneal thickness profile across an 8-mm chord along the horizontal meridian was generated at 0.5-mm intervals. Univariate and multivariate regression analyses were used to assess any predictable age-related differences, especially in the peripheral cornea.