Estimating the variability in the risk of infection for hepatitis C in the Glasgow injecting drug user population

AJ Sutton, S.A. McDonald, Norah Palmateer, A. Taylor, Sharon Hutchinson

Research output: Contribution to journalArticle

Abstract

Glasgow (Scotland's largest city) has a high prevalence of injecting drug use and has one of the highest prevalences of hepatitis C virus (HCV) infection in injecting drug users (IDUs) in Western Europe. HCV prevalence data from surveys of Glasgow's IDUs from 1990 to 2007 were utilized and a model was applied that described the prevalence of HCV as a function of the rate (force) of infection. Force-of-infection estimates for HCV that may vary over time and injecting career length over a range of variables were investigated. New initiates to injecting were found to be at increased risk of HCV infection, with being recruited from a street location and reporting injecting in prison leading to a significant increase in the risk of infection in new initiates. These results indicate areas of importance for the planning of public health measures that target the IDU population.
Original languageEnglish
Pages (from-to)2190-2198
Number of pages9
JournalEpidemiology and Infection
Volume140
Issue number12
DOIs
Publication statusPublished - Dec 2012

Keywords

  • hepatitis
  • infectious disease
  • injecting drug users
  • mathematical modelling
  • epidemiology

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