Glasgow (Scotland's largest city) has a high prevalence of injecting drug use and has one of the highest prevalences of hepatitis C virus (HCV) infection in injecting drug users (IDUs) in Western Europe. HCV prevalence data from surveys of Glasgow's IDUs from 1990 to 2007 were utilized and a model was applied that described the prevalence of HCV as a function of the rate (force) of infection. Force-of-infection estimates for HCV that may vary over time and injecting career length over a range of variables were investigated. New initiates to injecting were found to be at increased risk of HCV infection, with being recruited from a street location and reporting injecting in prison leading to a significant increase in the risk of infection in new initiates. These results indicate areas of importance for the planning of public health measures that target the IDU population.
- infectious disease
- injecting drug users
- mathematical modelling
Sutton, AJ., McDonald, S. A., Palmateer, N., Taylor, A., & Hutchinson, S. (2012). Estimating the variability in the risk of infection for hepatitis C in the Glasgow injecting drug user population. Epidemiology and Infection, 140(12), 2190-2198. https://doi.org/10.1017/S0950268812000489