TY - JOUR
T1 - Effectiveness of national and subnational infection prevention and control interventions in high-income and upper-middle-income countries: a systematic review
AU - Price, Lesley
AU - MacDonald, Jennifer
AU - Melone, Lynn
AU - Howe, Tracey
AU - Flowers, Paul
AU - Currie, Kay
AU - Curran, Evonne
AU - Ness, Valerie
AU - Waddell, Debbie
AU - Manoukian, Sarkis
AU - McFarland, Agi
AU - Kilpatrick, Claire
AU - Storr, Julie
AU - Twyman, Anthony
AU - Allegranzi, Benedetta
AU - Reilly, Jacqui
N1 - Acceptance email in SAN
VoR title is: 'Effectiveness of national and subnational infection prevention and control interventions in high-income and upper-middle-income countries: a systematic review'
AAM: 6m embargo
See email from L. Haahr re copyright agreement (WHO has copyright) 28-8-17
PY - 2018/5/1
Y1 - 2018/5/1
N2 - Evidence-based guidance for national infection prevention and control (IPC) programmes is needed to support national and global capacity building to reduce healthcare-associated infection and antimicrobial resistance. This systematic review evaluated the evidence on the effectiveness of IPC interventions implemented at national or sub-national level to inform the development of World Health Organization’s guidelines on the core components of national IPC programmes. CENTRAL, CINAHL, EMBASE, MEDLINE, and WHO IRIS were searched from January 1, 2000 to April 19, 2017. Twenty-nine studies meeting the eligibility criteria were categorised according to intervention type: multimodal; care bundles; policies; and surveillance, monitoring, and feedback. There was evidence of effectiveness in all categories but the best quality evidence was on multimodal interventions and surveillance, monitoring, and feedback. We call for improvements in study design, reporting of research and robust evidence, in particular from low income countries, to strengthen the uptake and international relevance of IPC interventions.
AB - Evidence-based guidance for national infection prevention and control (IPC) programmes is needed to support national and global capacity building to reduce healthcare-associated infection and antimicrobial resistance. This systematic review evaluated the evidence on the effectiveness of IPC interventions implemented at national or sub-national level to inform the development of World Health Organization’s guidelines on the core components of national IPC programmes. CENTRAL, CINAHL, EMBASE, MEDLINE, and WHO IRIS were searched from January 1, 2000 to April 19, 2017. Twenty-nine studies meeting the eligibility criteria were categorised according to intervention type: multimodal; care bundles; policies; and surveillance, monitoring, and feedback. There was evidence of effectiveness in all categories but the best quality evidence was on multimodal interventions and surveillance, monitoring, and feedback. We call for improvements in study design, reporting of research and robust evidence, in particular from low income countries, to strengthen the uptake and international relevance of IPC interventions.
KW - infection prevention
KW - antimicrobial resistance
KW - healthcare associated infection
U2 - 10.1016/S1473-3099(17)30479-6
DO - 10.1016/S1473-3099(17)30479-6
M3 - Article
VL - 18
SP - e159 - e171
JO - The Lancet Infectious Diseases
JF - The Lancet Infectious Diseases
SN - 1473-3099
IS - 5
ER -