Effectiveness of interventions to improve the public’s antimicrobial resistance awareness and behaviours associated with prudent use of antimicrobials: a systematic review

Lesley Price, Lucyna Gozdzielewska, Mairi Young, Fraser Smith, Jennifer MacDonald, Joanna McParland, Lynn Williams, Darren Langdridge, Mark Davis, Paul Flowers

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Abstract

Background
A global antimicrobial resistance (AMR) awareness intervention targeting the general public has been prioritized.

Objectives
To evaluate the effectiveness of interventions that aim to change AMR awareness and subsequent stewardship behaviours amongst the public.

Methods
Five databases were searched between 2000 and 2016 for interventions to change the public’s AMR awareness and/or antimicrobial stewardship behaviours. Study designs meeting the Cochrane Effective Practice and Organization of Care (EPOC) criteria, non-controlled before-and-after studies and prospective cohort studies were considered eligible. Participants recruited from healthcare settings and studies measuring stewardship behaviours of healthcare professionals were excluded. Quality of studies was assessed using EPOC risk of bias criteria. Data were extracted and synthesized narratively. Registration: PROSPERO international prospective register of systematic reviews (PROSPERO 2016: CRD42016050343).

Results
Twenty studies were included in the review with nine meeting the EPOC criteria. The overall risk of bias was high. Nineteen studies were conducted in high-income countries. Mass media interventions were most common (n¿=¿7), followed by school-based (n¿=¿6) and printed material interventions (n¿=¿6). Seventeen studies demonstrated a significant effect on changing knowledge, attitudes or the public’s antimicrobial stewardship behaviours. Analysis showed that interventions targeting schoolchildren and parents have notable potential, but for the general public the picture is less clear.

Conclusions
Our work provides an in-depth examination of the effectiveness of AMR interventions for the public. However, the studies were heterogeneous and the quality of evidence was poor. Well-designed, experimental studies on behavioural outcomes of such interventions are required.
Original languageEnglish
JournalJournal of Antimicrobial Chemotherapy
DOIs
Publication statusPublished - 14 Mar 2018

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Organizations
Delivery of Health Care
Mass Media
Cohort Studies
Parents
Databases
Prospective Studies

Keywords

  • antimicrobial resistance
  • public awareness
  • AMR

Cite this

@article{a4ee46320a714b4894b89f6f00a6415f,
title = "Effectiveness of interventions to improve the public’s antimicrobial resistance awareness and behaviours associated with prudent use of antimicrobials: a systematic review",
abstract = "BackgroundA global antimicrobial resistance (AMR) awareness intervention targeting the general public has been prioritized.ObjectivesTo evaluate the effectiveness of interventions that aim to change AMR awareness and subsequent stewardship behaviours amongst the public.MethodsFive databases were searched between 2000 and 2016 for interventions to change the public’s AMR awareness and/or antimicrobial stewardship behaviours. Study designs meeting the Cochrane Effective Practice and Organization of Care (EPOC) criteria, non-controlled before-and-after studies and prospective cohort studies were considered eligible. Participants recruited from healthcare settings and studies measuring stewardship behaviours of healthcare professionals were excluded. Quality of studies was assessed using EPOC risk of bias criteria. Data were extracted and synthesized narratively. Registration: PROSPERO international prospective register of systematic reviews (PROSPERO 2016: CRD42016050343).ResultsTwenty studies were included in the review with nine meeting the EPOC criteria. The overall risk of bias was high. Nineteen studies were conducted in high-income countries. Mass media interventions were most common (n¿=¿7), followed by school-based (n¿=¿6) and printed material interventions (n¿=¿6). Seventeen studies demonstrated a significant effect on changing knowledge, attitudes or the public’s antimicrobial stewardship behaviours. Analysis showed that interventions targeting schoolchildren and parents have notable potential, but for the general public the picture is less clear.ConclusionsOur work provides an in-depth examination of the effectiveness of AMR interventions for the public. However, the studies were heterogeneous and the quality of evidence was poor. Well-designed, experimental studies on behavioural outcomes of such interventions are required.",
keywords = "antimicrobial resistance, public awareness, AMR",
author = "Lesley Price and Lucyna Gozdzielewska and Mairi Young and Fraser Smith and Jennifer MacDonald and Joanna McParland and Lynn Williams and Darren Langdridge and Mark Davis and Paul Flowers",
note = "Acceptance from webpage AAM: 12m embargo Note: author has attached research data (supplementary data file) in Other Files field. ET",
year = "2018",
month = "3",
day = "14",
doi = "10.1093/jac/dky076",
language = "English",
journal = "Journal of Antimicrobial Chemotherapy",
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TY - JOUR

T1 - Effectiveness of interventions to improve the public’s antimicrobial resistance awareness and behaviours associated with prudent use of antimicrobials: a systematic review

AU - Price, Lesley

AU - Gozdzielewska, Lucyna

AU - Young, Mairi

AU - Smith, Fraser

AU - MacDonald, Jennifer

AU - McParland, Joanna

AU - Williams, Lynn

AU - Langdridge, Darren

AU - Davis, Mark

AU - Flowers, Paul

N1 - Acceptance from webpage AAM: 12m embargo Note: author has attached research data (supplementary data file) in Other Files field. ET

PY - 2018/3/14

Y1 - 2018/3/14

N2 - BackgroundA global antimicrobial resistance (AMR) awareness intervention targeting the general public has been prioritized.ObjectivesTo evaluate the effectiveness of interventions that aim to change AMR awareness and subsequent stewardship behaviours amongst the public.MethodsFive databases were searched between 2000 and 2016 for interventions to change the public’s AMR awareness and/or antimicrobial stewardship behaviours. Study designs meeting the Cochrane Effective Practice and Organization of Care (EPOC) criteria, non-controlled before-and-after studies and prospective cohort studies were considered eligible. Participants recruited from healthcare settings and studies measuring stewardship behaviours of healthcare professionals were excluded. Quality of studies was assessed using EPOC risk of bias criteria. Data were extracted and synthesized narratively. Registration: PROSPERO international prospective register of systematic reviews (PROSPERO 2016: CRD42016050343).ResultsTwenty studies were included in the review with nine meeting the EPOC criteria. The overall risk of bias was high. Nineteen studies were conducted in high-income countries. Mass media interventions were most common (n¿=¿7), followed by school-based (n¿=¿6) and printed material interventions (n¿=¿6). Seventeen studies demonstrated a significant effect on changing knowledge, attitudes or the public’s antimicrobial stewardship behaviours. Analysis showed that interventions targeting schoolchildren and parents have notable potential, but for the general public the picture is less clear.ConclusionsOur work provides an in-depth examination of the effectiveness of AMR interventions for the public. However, the studies were heterogeneous and the quality of evidence was poor. Well-designed, experimental studies on behavioural outcomes of such interventions are required.

AB - BackgroundA global antimicrobial resistance (AMR) awareness intervention targeting the general public has been prioritized.ObjectivesTo evaluate the effectiveness of interventions that aim to change AMR awareness and subsequent stewardship behaviours amongst the public.MethodsFive databases were searched between 2000 and 2016 for interventions to change the public’s AMR awareness and/or antimicrobial stewardship behaviours. Study designs meeting the Cochrane Effective Practice and Organization of Care (EPOC) criteria, non-controlled before-and-after studies and prospective cohort studies were considered eligible. Participants recruited from healthcare settings and studies measuring stewardship behaviours of healthcare professionals were excluded. Quality of studies was assessed using EPOC risk of bias criteria. Data were extracted and synthesized narratively. Registration: PROSPERO international prospective register of systematic reviews (PROSPERO 2016: CRD42016050343).ResultsTwenty studies were included in the review with nine meeting the EPOC criteria. The overall risk of bias was high. Nineteen studies were conducted in high-income countries. Mass media interventions were most common (n¿=¿7), followed by school-based (n¿=¿6) and printed material interventions (n¿=¿6). Seventeen studies demonstrated a significant effect on changing knowledge, attitudes or the public’s antimicrobial stewardship behaviours. Analysis showed that interventions targeting schoolchildren and parents have notable potential, but for the general public the picture is less clear.ConclusionsOur work provides an in-depth examination of the effectiveness of AMR interventions for the public. However, the studies were heterogeneous and the quality of evidence was poor. Well-designed, experimental studies on behavioural outcomes of such interventions are required.

KW - antimicrobial resistance

KW - public awareness

KW - AMR

U2 - 10.1093/jac/dky076

DO - 10.1093/jac/dky076

M3 - Article

JO - Journal of Antimicrobial Chemotherapy

JF - Journal of Antimicrobial Chemotherapy

SN - 0305-7453

ER -