Effectiveness of artificial tears in the management of evaporative dry eye

Louise Madden, Alan Tomlinson, Edward Pearce, Vincenzi Papa

Research output: Contribution to journalArticlepeer-review

63 Citations (Scopus)


The aim of this study was to compare the efficacies of sodium hyaluronate, hydroxypropyl methylcellulose (HPMC), and a new oil-in-water emulsion (Emustil unidose; SIFI) in the management of lipid-deficient dry eye. A significant reduction in evaporation and improvement in symptoms in all therapy groups were found from baseline to 90 days. However, no significant effect was seen on TTR for any group. The emulsion drops were shown to perform best, improving tear stability, and decreasing osmolarity and corneal staining. These results are consistent with improvements in the lipid layer of the tear film as a result of prolonged use of emulsion drops.
Original languageEnglish
Pages (from-to)1-5
Number of pages5
Issue number1
Publication statusPublished - Jan 2012


  • vision sciences
  • dry eye disease
  • artificial tears


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