Effect of polymer strengtheners on the local environment of biocompatible glass as probed by fluorescence

Graham Hungerford, Mariana Amaro, Pedro Martins, Isabel Ferreira, Mahesh Uttamlal, A. Sheila Holmes-Smith

    Research output: Contribution to journalArticle

    Abstract

    Mixed silica–calcite matrices were prepared by developing a “low” temperature (sol–gel) method in presence of several biocompatible polymers, thus providing samples with adequate porosity for the flow of biological fluids and also mechanically robust. In order to analyse and characterise the sample’s microenvironments, the highly solvatochromic probe Nile red was used, which enabled the role of polymer addition upon local environmental effects in the host media to be elucidated. The polymers used were polyethylene glycol, polymethylmethacrylate and polyethylene. Each matrix was also characterized with respect to microstructure, morphology and pore size via the use of X-ray diffractometry and scanning electron microscopy.

    Original languageEnglish
    Pages (from-to)297-303
    Number of pages7
    JournalJournal of Fluorescence
    Volume18
    Issue number2
    DOIs
    Publication statusPublished - 1 Dec 2007

    Keywords

    • biocompatible glass
    • fluorescence
    • scanning electron microscopy

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